Nutlin

Results: 12



#Item
1Tumor suppressor genes / Apoptosis / Programmed cell death / Gene expression / Nutlin / P53 / Mdm2 / P21 / P73 / Biology / Medicine / Proteins

Citation: Cell Death and Disease[removed], e294; doi:[removed]cddis[removed] & 2012 Macmillan Publishers Limited All rights reserved[removed]www.nature.com/cddis Human neuroblastoma cells with acquired resistance

Add to Reading List

Source URL: www.nature.com

Language: English - Date: 2012-04-05 05:56:19
2Proteins / RNA / Apoptosis / Programmed cell death / Mdm2 / P53 / Non-coding RNA / Nutlin / NUMB / Biology / Genetics / MicroRNA

Mir-660 is downregulated in lung cancer patients and its replacement inhibits lung tumorigenesis by targeting MDM2-p53 interaction

Add to Reading List

Source URL: www.nature.com

Language: English - Date: 2014-12-11 08:43:03
3Proteins / Apoptosis / Programmed cell death / Tumor suppressor genes / Carcinogenesis / P53 / Mdm2 / Nutlin / P21 / Biology / Medicine / Cell biology

The Hsp90 inhibitor 17-(allylamino)-17-demethoxygeldanamycin increases cisplatin antitumor activity by inducing p53-mediated apoptosis in head and neck cancer

Add to Reading List

Source URL: www.nature.com

Language: English - Date: 2013-12-12 11:21:15
4Gene expression / Apoptosis / Programmed cell death / Mdm2 / P53 / Homeobox protein NANOG / Nutlin / Cellular differentiation / Bcl-2-associated X protein / Biology / Proteins / Transcription factors

p53 is active in murine stem cells and alters the transcriptome in a manner that is reminiscent of mutant p53

Add to Reading List

Source URL: www.nature.com

Language: English - Date: 2015-02-26 08:33:04
5Proteins / Apoptosis / Immune system / Tumor suppressor genes / Mdm2 / Nutlin / P53 / P21 / Bcl-2-associated X protein / Biology / Cell biology / Programmed cell death

Citation: Cell Death and Disease[removed], e148; doi:[removed]cddis[removed] & 2011 Macmillan Publishers Limited All rights reserved[removed]www.nature.com/cddis Disruption of the MDM2–p53 interaction strongly

Add to Reading List

Source URL: www.nature.com

Language: English - Date: 2011-04-21 07:08:27
6Apoptosis / Proteins / Bcl-2-associated X protein / Bcl-2 family / Bcl-2 / Nutlin / Epstein–Barr virus / Mdm2 / Fas receptor / Biology / Cell biology / Programmed cell death

Treatment with a BH3 mimetic overcomes the resistance of latency III EBV (+) cells to p53-mediated apoptosis

Add to Reading List

Source URL: www.nature.com

Language: English - Date: 2011-07-28 06:01:07
7Tumor suppressor genes / Proteins / Carcinogenesis / Apoptosis / Programmed cell death / Nutlin / P53 / Neuroblastoma / P16 / Biology / Medicine / Oncology

Citation: Cell Death and Disease[removed], e243; doi:[removed]cddis[removed] & 2011 Macmillan Publishers Limited All rights reserved[removed]www.nature.com/cddis Adaptation of cancer cells from different entities to

Add to Reading List

Source URL: www.nature.com

Language: English - Date: 2011-12-15 05:58:36
8Apoptosis / Programmed cell death / Nutlin / Mdm2 / P53 / P21 / Hsp90 inhibitors / Hsp90 / NUMB / Biology / Cell biology / Proteins

Citation: Cell Death and Disease[removed], e156; doi:[removed]cddis[removed] & 2011 Macmillan Publishers Limited All rights reserved[removed]www.nature.com/cddis Blockade of Hsp90 by 17AAG antagonizes MDMX

Add to Reading List

Source URL: www.nature.com

Language: English
9Proteins / Apoptosis / Programmed cell death / RNA / Mdm2 / P53 / Nutlin / P21 / Mir-200 / Biology / Genetics / MicroRNA

Mir-509-5p joins the Mdm2/p53 feedback loop and regulates cancer cell growth

Add to Reading List

Source URL: www.nature.com

Language: English - Date: 2014-08-21 08:36:46
10Medicine / Apoptosis / Programmed cell death / Tumor suppressor genes / P53 / Mdm2 / Neuroblastoma / Nutlin / Ataxia telangiectasia mutated / Biology / Proteins / Cell biology

Pediatric Subcommittee of the Oncologic Drugs Advisory Committee The MDM2 antagonist RO5503781 Gwen L Nichols MD Translational Medicine Oncology Roche Pharmaceutical Research and Early Development

Add to Reading List

Source URL: www.fda.gov

Language: English
UPDATE