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Hsp90
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61	Targeting β-tubulin:CCT-β complexes incurs Hsp90- and VCP-related protein degradation and induces ER stress-associated apoptosis by triggering capacitative Ca2+ entry, mitochondrial perturbatio Add to Reading List Source URL: www.nature.com Language: English - Date: 2012-11-29 06:00:13 Proteins Apoptosis Heat shock proteins Cancer research Hsp90 inhibitors Hsp90 Apoptosome Hsp70 Tubulin Biology Cell biology Programmed cell death
62	OPEN Citation: Cell Death and Disease[removed], e1666; doi:[removed]cddis[removed] & 2015 Macmillan Publishers Limited All rights reserved[removed]www.nature.com/cddis Add to Reading List Source URL: www.nature.com Language: English - Date: 2015-02-26 08:32:57 Apoptosis Proteins Immune system Heat shock proteins Hsp90 Fas receptor Caspase 3 TRAIL Tumor necrosis factor-alpha Biology Cell biology Programmed cell death
63	Small molecule sensitization to TRAIL is mediated via nuclear localization, phosphorylation and inhibition of chaperone activity of Hsp27 Add to Reading List Source URL: www.nature.com Language: English - Date: 2013-10-31 10:54:37 Heat shock proteins Apoptosis Programmed cell death Protein kinases Hsp27 Mitogen-activated protein kinase Tumor necrosis factor-alpha P53 Hsp90 Biology Cell biology Proteins
64	The Hsp90 inhibitor 17-(allylamino)-17-demethoxygeldanamycin increases cisplatin antitumor activity by inducing p53-mediated apoptosis in head and neck cancer Add to Reading List Source URL: www.nature.com Language: English - Date: 2013-12-12 11:21:15 Proteins Apoptosis Programmed cell death Tumor suppressor genes Carcinogenesis P53 Mdm2 Nutlin P21 Biology Medicine Cell biology
65	Defect in HSP90 expression in highly differentiated human CD8+ T lymphocytes Add to Reading List Source URL: www.nature.com Language: English - Date: 2014-06-12 12:19:19 Hsp90 AKT CD8 CD28 Hsp90 inhibitors T cells Biology Cell biology
66	UDP glucuronosyltransferase 1A expression levels determine the response of colorectal cancer cells to the heat shock protein 90 inhibitor ganetespib Add to Reading List Source URL: www.nature.com Language: English - Date: 2014-09-11 08:36:29 Proteins Cancer research Hsp90 inhibitors Hsp90 Heat shock protein Geldanamycin NVP-AUY922 Chaperone Breast cancer Chemistry Medicine Organic chemistry
67	Specific SKN-1/Nrf Stress Responses to Perturbations in Translation Elongation and Proteasome Activity Xuan Li1,2,3, Olli Matilainen4, Congyu Jin4, Kira M. Glover-Cutter1,2, Carina I. Holmberg4, T. Keith Blackwell1,2 1 Add to Reading List Source URL: blackwellweb.joslin.harvard.edu Language: English - Date: 2011-12-08 12:31:17 Proteasome Hsp90 Gene expression Unfolded protein response RNA Ubiquitin Arc Chaperone Biology Proteins RNA interference
68	Citation: Cell Death and Disease[removed], e156; doi:[removed]cddis[removed] & 2011 Macmillan Publishers Limited All rights reserved[removed]www.nature.com/cddis Blockade of Hsp90 by 17AAG antagonizes MDMX Add to Reading List Source URL: www.nature.com Language: English Apoptosis Programmed cell death Nutlin Mdm2 P53 P21 Hsp90 inhibitors Hsp90 NUMB Biology Cell biology Proteins
69	ACTIVITY OF THE HSP90 INHIBITOR, AT13387, IN ALK-DRIVEN TUMOR MODELS. Nicola Wallis, Tomoko Smyth, Joanne Munck, Ana Rodriguez-Lopez, Victoria Lock, Rachel McMenamin, Neil Thompson & John Lyons Astex Pharmaceuticals, 436 Add to Reading List Source URL: astx.com Language: English - Date: 2012-12-17 16:09:22 Organofluorides Oncology Crizotinib Piperidines Pyrazoles Pyridines ALK inhibitor Anaplastic lymphoma kinase Non-small-cell lung carcinoma Lung cancer Medicine Chemistry
70	Combination of HSP90 inhibitor onalespib (AT13387) with crizotinib to treat or delay resistance in NSCLC: Preclinical and Clinical Investigations. Harold Keer, Tomoko Smyth, Aurelie Courtin, Keisha Hearn, John Lyons, Nic Add to Reading List Source URL: astx.com Language: English Oncology Organofluorides Crizotinib Piperidines Pyrazoles Pyridines Anaplastic lymphoma kinase Hsp90 inhibitors Hsp90 Medicine Chemistry Lung cancer

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