Short Article An endosiRNA-Based Repression Mechanism Counteracts Transposon Activation during Global DNA Demethylation in Embryonic Stem Cells Graphical Abstract

Source URL: www.umassmed.edu

Hanover_3.2_project_ProLignin_Liitia

Source URL: www.woodwisdom.net

• Chemistry
• Papermaking
• Lignin
• Phenylpropanoids
• Functional groups
• Pulp and paper industry
• Ether
• Organosolv
• Hydroxide
• Phenol
• Demethylation

REPORTS passive 5mC depletion (fig. S23) (18), which may contribute to the partial demethylation observed in Tet1 and Tet2 knockdown PGCLCs. Thus, whereas in zygotes 5mC reprogramming is mechanistically compartmentalized

Source URL: www.columbia.edu

Discovery of the Mechanism by which Mitochondria are Eliminated from Red Blood Cells and the Involvement of Alternative Autophagy DNA Demethylation-Dependent Regulation of Hepatic Lipid Metabolism Shigeomi Shimizu

Source URL: www.tmd.ac.jp

PL-ISSNprint), ISSNonline) Folia Biologica (Kraków), vol), No 2 Ó Institute of Systematics and Evolution of Animals, PAS, Kraków, 2014

Source URL: www.isez.pan.krakow.pl

• DNA
• Posttranslational modification
• Molecular genetics
• Gene expression
• Methylation
• DNA methylation
• Reprogramming
• Cellular differentiation
• DNA demethylation
• Genetics
• Biology
• Epigenetics

Nuclear factor Y-mediated H3K27me3 demethylation of the SOC1 locus orchestrates flowering responses of Arabidopsis Xingliang Hou, Jiannan Zhou, Chang Liu, Lu Liu, Lisha Shen & Hao Yu

Source URL: www.nus.edu.sg

• Transcription factors
• Gene expression
• Organism
• Biology
• Genetics
• Epigenetics

Mitochondrial DNA copy number is regulated by DNA methylation and demethylation of POLGA in stem and cancer cells and their differentiated progeny

Source URL: www.nature.com

• Stem cells
• Developmental biology
• Genomics
• Biotechnology
• Cellular differentiation
• Mitochondrial DNA
• Induced pluripotent stem cell
• DNA methylation
• Methylated DNA immunoprecipitation
• Biology
• Genetics
• Epigenetics

DNA demethylation activity over time and safety of 3 different dose-escalation regimens of SGI-110, a novel subcutaneous (SQ) hypomethylating agent (HMA), in the treatment of relapsed/refractory patients with MDS and AML

Source URL: astx.com

• Pharmacology
• Azacitidine
• lactams
• Chemistry
• Decitabine
• Hypomethylating agent
• Nucleosides
• Triazines
• Medicine

Study of the correlation of baseline biomarkers and DNA demethylation to clinical responses in a phase 1/2, randomized study of SGI-110, a novel subcutaneous hypomethylating agent in the treatment of relapsed/refractory

Source URL: astx.com

• Medicine
• Epigenetics
• Biology
• Acute leukemia
• Myeloid leukemia
• Azacitidine
• Acute myeloid leukemia
• Hypomethylating agent
• Decitabine
• Oncology
• Nucleosides
• Triazines

1442 Determinants of Demethylation and Clinical Response In AML Patients Treated With SGI-110, a Novel Subcutaneous (SQ) Hypomethylating Agent (HMA) In a Phase 1 Study Woonbok Chung, PhD1, Pietro Taverna, PhD2, John F L

Source URL: astx.com

• P53
• Programmed cell death
• Proteins
• Biology
• Cell biology
• Apoptosis