Smoothened

Results: 10



#Item
1Biology / Cell biology / Cell signaling / Organelles / Hedgehog signaling pathway / Developmental biology / Smoothened / Cilium / Intraflagellar transport / Ciliogenesis / Patched / KIF3A

Hedgehog Signaling Regulates the Ciliary Transport of Odorant Receptors in Drosophila Gonzalo Manuel Sanchez, Liza Alkhori Franzén, Eduardo Hatano, Sebastian Schultz, Anujaianthi Kuzhandaivel, Shadi Jafari, Björn Grans

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Source URL: liu.diva-portal.org

Language: English - Date: 2016-03-15 08:58:50
2Cell biology / Biology / Cell signaling / Proteins / Hedgehog signaling pathway / Morphogens / Smoothened / Cyclopamine / Vismodegib / Sonic hedgehog / Small molecule / IHH

article published online: 8 january 2012 | doi: nchembio.765 Oxysterols are allosteric activators of the oncoprotein Smoothened

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Source URL: rohatgi.stanford.edu

Language: English - Date: 2013-02-15 12:38:42
3Cell signaling / Organelles / Smoothened / Ptc1 / Hedgehog signaling pathway / Sonic hedgehog / Cilium / 3T3 cells / Neural tube

Patched1 Regulates Hedgehog Signaling at the Primary Cilium Rajat Rohatgi et al. Science 317, ); DOI: scienceThis copy is for your personal, non-commercial use only.

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Source URL: rohatgi.stanford.edu

Language: English - Date: 2013-02-15 13:04:57
4Hedgehog signaling pathway / Histopathology / Cell signaling / Vismodegib / Smoothened / Basal-cell carcinoma / Breast cancer / Melanoma / Skin cancer / Medicine / Biology / Oncology

Skin tumors develop specific mutations to resist drug, researchers say

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Source URL: medicalxpress.com

Language: English - Date: 2015-04-13 14:02:44
5Hedgehog signaling pathway / Histopathology / Organochlorides / Sulfones / Vismodegib / Medulloblastoma / Smoothened / Basal-cell carcinoma / Patched / Biology / Cell biology / Cell signaling

Vismodegib Briefing Package: Pediatric ODAC Subcommittee Meeting (1 November 2011)

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Source URL: www.fda.gov

Language: English
6Organochlorides / Histopathology / Hedgehog signaling pathway / Sulfones / Vismodegib / Medulloblastoma / Basal-cell carcinoma / Smoothened / Patched / Medicine / Biology / Oncology

Vismodegib Pediatric Development

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Source URL: www.fda.gov

Language: English
7Spiro compounds / Teratogens / Cell signaling / Cyclopamine / Pseudomonas aeruginosa / Patched / Smoothened / Veratrum californicum / Cyclopia / Biology / Hedgehog signaling pathway / Alcohols

news and views side is holoprosencephaly — a disease associated with mutations in the human version of the fruitfly’s hedgehog gene that inactivate it4–6. The Hedgehog pathway is important in the development of the

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Source URL: people.csail.mit.edu

Language: English - Date: 2004-12-08 14:54:40
8Proteins / Hedgehog signaling pathway / Cell signaling / GLI2 / GLI3 / GLI1 / KIF3A / Patched / Smoothened / Biology / Transcription factors / Genes

letters Primary cilia can both mediate and suppress Hedgehog pathway–dependent tumorigenesis © 2009 Nature America, Inc. All rights reserved.

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Source URL: www.nature.com

Language: English - Date: 2010-02-12 11:00:06
9Atypical teratoid rhabdoid tumor / Radiation therapy / Medicine / Brain tumor / Medulloblastoma

PBTC-025 v1.0 Version Date: [removed]Protocol Abstract and Schema Phase I study of the Smoothened (SMO) antagonist GDC-0449 for recurrent or refractory medulloblastoma

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Source URL: www.pbtc.org

Language: English - Date: 2009-02-17 14:38:02
10Transcription factors / Proteins / Genes / Hedgehog signaling pathway / GLI2 / GLI1 / Cyclopamine / Sonic hedgehog / Smoothened / Biology / Cell biology / Cell signaling

BioResearch Open Access Volume 3, Number 2, April 2014 ª Mary Ann Liebert, Inc.

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Source URL: www.ncbi.nlm.nih.gov

Language: English
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