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Carcinogenesis / Tumor suppressor genes / Oncogenes / Gynaecological cancer / KRAS / COSMIC cancer database / P53 / Breast cancer / Mucinous tumor / Medicine / Oncology / Biology


Targeted deep sequencing of mucinous ovarian tumors reveals multiple overlapping RAS-pathway activating mutations in borderline and cancerous neoplasms
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City

Tuebingen / Mayo / Heidelberg / Vancouver / Rochester / A TMA / Oncology / /

Company

Agilent / TP53 / Ryland / Stephens / Forbes SA / PTEN / Cox / Creative Commons / Google / /

Country

Canada / Germany / United States / /

Currency

pence / /

/

Event

M&A / /

Facility

University of British Columbia / BC Cancer Agency Research Centre / University of Heidelberg / Mayo Clinic / Laboratory Medicine / Tuebingen University Hospital / Institute of Pathology / /

IndustryTerm

Data processing / tumor bank / quality control processing / online submission / /

MedicalCondition

endometrial stromal sarcoma / Ovarian Cancer / mucinous ovarian carcinoma / ovarian serous low malignant potential tumors / low-grade serous ovarian cancer / MBOT Carcinoma / metastatic disease / Mackenzie et al. BMC Cancer / HPV infection / together cancers / ovarian mucinous carcinomas / ovarian tumors / pancreatic solid-pseudopapillary neoplasm / breast carcinomas / early stage disease / mucinous ovarian cancer / ovarian mucinous carcinoma / epithelial ovarian cancer / breast cancer / recurrent disease / pancreatic ductal adenocarcinomas / esophageal cancers / early epithelial ovarian cancer / mucinous ovarian tumors / tumor / cancer / tumors / pancreatic and appendiceal tumors / rare metastasis / HPV / human cancer / III/IV epithelial ovarian cancer / primary ovarian mucinous tumors / mucinous ovarian and appendiceal carcinomas / Mucinous borderline tumor / ovarian carcinomas / MBOT Mackenzie et al. BMC Cancer / Mucinous borderline tumors TP53 / BMC Cancer / Pre-invasive ovarian mucinous tumors / Solid-pseudopapillary tumors / primary ovarian tumor / borderline tumors / ovarian low-grade serous/serous borderline tumor / Primary and metastatic mucinous adenocarcinomas / acute myeloid leukemia / mucinous ovarian cancers / esophageal adenocarcinoma / mucinous ovarian tumours / OVCARE tumor / mucinous carcinoma / ovarian surface epithelial tumors / Hidalgo M. Pancreatic cancer / mucinous carcinomas / appendiceal epithelial tumors / Primary mucinous ovarian carcinomas / J Cancer / primary ovarian tumors / primary melanocytic tumours / advanced ovarian carcinomas / III epithelial ovarian cancer / primary and metastatic mucinous tumors / invasive carcinomas / complete cancer / mucinous tumor / MS / ovarian carcinoma / lung cancers / mucinous borderline tumors / mucinous tumors / adenocarcinomas / squamous cell lung cancers / disease / benign cysts / ovarian mucinous and other peritoneal mucinous tumors / tumour / epithelial ovarian carcinoma / squamous cell cancers / cancerous neoplasms Robertson Mackenzie1 / J Gynecol Cancer / Mody K / mucinous cancers / metastatic mucinous carcinomas / carcinomas / Borderline Tumor / mucinous tumours / single carcinoma / relatively rare tumor / /

MedicalTreatment

chemotherapy / /

Organization

University of Heidelberg / VGH / UBC Hospital Foundation / College of American Pathologists / BC Cancer Agency Research Centre / Institute of Pathology / BC Cancer Foundation / University of British Columbia / Vancouver / American Society / Tuebingen University Hospital / Department of Pathology and Laboratory Medicine / /

Person

Sanger / Ann Oncol / Ion Torrent / Shih Ie / Ion-Torrent Cancer Hotspot Sequencing / /

Position

author / driver / Hunter / Fisher / Porter / /

Product

SC / paclitaxel / 20pM / CL / /

ProgrammingLanguage

DC / /

ProvinceOrState

British Columbia / /

RadioStation

Oza AM / Gown AM / Swart AM / Dulak AM / CBG / /

Technology

gene amplification / High Sensitivity DNA chips / chemotherapy / hybridization / 316 chips / quantified using Agilent High Sensitivity DNA chips / /

URL

http /

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