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Metabolic pathways / Chemistry / Steroids / 7-Dehydrocholesterol reductase / Smith-Lemli-Opitz syndrome / Cholesterol / 7-Dehydrocholesterol / Mevalonate pathway / Statin / Biology / Sterols / Nutrition


Nanostructure-initiator mass spectrometry (NIMS) imaging of brain cholesterol metabolites in Smith-Lemli-Opitz syndrome
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Document Date: 2013-12-10 15:01:42

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Santa Clara / MANCHESTER / La Jolla / St. Louis / /

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Sonic / Nordstrom / Sigma Aldrich / GE / Proc Natl Acad Sci U S A / Excess Ag / Leica Microsystems Inc. / Elsevier Ltd. / Suzuki / Russell AE / /

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United States / /

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Research Institute / C terminus / Arch Gen Psychiatry / Eunice Kennedy Shriver National Institute of Child Health / California Institute of Regenerative Medicine / University of California / /

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nitrogen gas / piranha solution / stream end products / imaging / gas chromatography/ mass spectrometry / brain imaging / tissue imaging / gas chromatography/mass spectrometry / Web version / /

MedicalCondition

gene/environment-induced cholesterol deficiency / neurological disorders / developmental disorders / Preputial gland tumor / Huntington disease / SLOS disease / disorder / both cholesterol deficiency / Smith-Lemli-Opitz syndrome / MS / autism spectrum disorders / Alzheimer’s disease / brain dysfunction / SmithLemli-Opitz syndrome / disease / autism / RSH/Smith-Lemli-Opitz syndrome / neurodegenerative diseases / Opitz syndrome / Smith-Lemli-Optiz syndrome / RSH/Smith-LemliOpitz syndrome / disorders / /

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pharmacotherapy / /

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Northen MT / /

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National Institute of Health / California Institute of Regenerative Medicine / Research Institute / Scripps Center for Mass Spectrometry / Department of Molecular Biology / Eunice Kennedy Shriver National Institute of Child Health and Development / Scripps Research Institute / Skaggs School of Pharmacy and Pharmaceutical Sciences / Eunice Kennedy Shriver National Institute of Child Health / Department of Health and Human Services / University of California / San Diego / /

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Eunice Kennedy Shriver / Ann Neurol / Kelley / Herman / Leoni V / /

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player in cerebellar development / representative / Porter / /

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SHH signaling / Dhcr7 / response / /

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Maryland / California / /

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Molecular Biology / /

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Genomics / Neuroscience / cell signaling / apoptosis / laser / gas chromatography / Regenerative Medicine / /

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