REVERSE ENGINEERING OF METABOLIC PATHWAYS FROM OBSERVED DATA USING GENETIC PROGRAMMING John R. Koza Biomedical Informatics, Department of Medicine Department of Electrical Engineering

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Information for Authors Information for Authors Metabolism and Nutrition in Oncology (MNO) is an open access journal covering all aspects of metabolic pathways in cancer. The journal investigates the pathophysiology of

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Nucleic Acids Research, 2006, Vol. 34, Database issue D511–D516 doi:nar/gkj128 MetaCyc: a multiorganism database of metabolic pathways and enzymes 5

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Genome Informatics 12: 312–Towards Simulation of Whole Metabolic Pathways in Human Erythrocyte

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3.5 year UK Space Agency funded PhD StudentshipChemolithotrophs on Mars: Metabolic pathways and Biosignatures Supervisory Team: Dr. Claire Cousins and Dr. Aubrey Zerkle (Univ. St Andrews) Project collaborato

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Seminar 2  Isotope tracing    13​ Q: ​ How many possible ​

Source URL: www.nilssonlab.se

• Chemistry
• Biochemistry
• Biology
• Metabolism
• Cellular respiration
• Metabolic pathways
• Anaplerotic reactions
• Citric acid cycle
• Biosynthesis
• Dehydrogenase
• Pyruvate kinase
• Alpha-Ketoglutaric acid

Seminar 1, Tuesday 8/3  Material and energy budget  1.​  In his studies of glycolysis in cancer, Otto Warburg noted that some tumors produce their own  weight in lactate in as little as 

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• Biology
• Biochemistry
• Chemistry
• Cellular respiration
• Metabolism
• Nutrition
• Metabolic pathways
• Coenzymes
• Glycolysis
• Nicotinamide adenine dinucleotide
• Adenosine triphosphate
• Carbohydrate metabolism

Ways to study metabolism – tradeoffs Course 2851 Principles of Metabolism Metabolism and endocrinology programme, Karolinska Institutet

Source URL: www.nilssonlab.se

• Biology
• Alternatives to animal testing
• In vitro
• Metabolism
• In vivo
• Biotechnology
• Research
• Cell biology
• Metabolic pathways

Le1 Introduction Le5 Metabolic networks and flux analysis Le2 Material and energy

Source URL: www.nilssonlab.se

• Biology
• Chemistry
• Nutrition
• Biochemistry
• Cellular respiration
• Metabolic pathways
• Citric acid cycle
• Exercise physiology
• Metabolism
• Carbohydrate
• Fatty acid
• Nutrient

Seminar 4  Measuring metabolism  For mass spectrometry problems, you can look up exact masses of metabolites and their ions of  metabolites in the METLIN database, metlin.scripps.edu; go to M

Source URL: www.nilssonlab.se

• Biochemistry
• Chemistry
• Biology
• Metabolism
• Metabolic pathways
• Fatty acids
• Cellular respiration
• Nutrition
• Beta oxidation
• Mevalonate pathway
• Fatty acid synthesis
• Acetyl-CoA