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Hsp90
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51	Evidence of AT13387 Activity in Gastrointestinal Stromal Tumor Models Presented at ECCO DUBLIN, Calif.--(BUSINESS WIRE)-- Astex Pharmaceuticals, Inc. (NASDAQ: ASTX), a pharmaceutical company dedicated to the discovery an Add to Reading List Source URL: astx.com Language: English Indoles Organofluorides Pfizer Pyrroles Sunitinib Lactams Gastrointestinal stromal tumor Hsp90 Imatinib Chemistry Organic chemistry Medicine
52	October 30, 2012 Astex Pharmaceuticals Reports 2012 Third Quarter Financial Results Dacogen Approved in the European Union for the Treatment of Elderly AML Initiated HSP90 Inhibitor AT13387 Clinical Trials in Prostate & Add to Reading List Source URL: astx.com Language: English Generally Accepted Accounting Principles Taxation Financial statements Financial accounting Financial markets Balance sheet Income tax in the United States Deferral Income tax Finance Accountancy Business
53	October 24, 2012 Astex Pharmaceuticals Announces Initiation of AT13387 Phase 2 Study in Non-Small Cell Lung Cancer DUBLIN, Calif., Oct. 24, 2012 (GLOBE NEWSWIRE) -- Astex Pharmaceuticals, Inc. (Nasdaq:ASTX), a pharmaceu Add to Reading List Source URL: astx.com Language: English Organofluorides Piperidines Lung cancer Crizotinib Pyrazoles Anaplastic lymphoma kinase Non-small-cell lung carcinoma Hsp90 Erlotinib Chemistry Organic chemistry Pfizer
54	July 22, 2013 Astex Pharmaceuticals Announces First Data Showing Early Combination Treatment of HSP90 Inhibitor AT13387 With Targeted Agents Delays Emergence of Resistance in Preclinical Models Data Presented at 8th Wor Add to Reading List Source URL: astx.com Language: English Organofluorides Alkynes Melanoma Organochlorides Vemurafenib Hsp90 Astex Targeted therapy Erlotinib Chemistry Organic chemistry Medicine
55	Do you know the Mode of Action of your drug? CaptiVate™ Identification of protein complexes and protein interactions in mammalian cells Unique service workflow produces complete data set. Identify all protein partners Add to Reading List Source URL: www.dualsystems.com Language: English - Date: 2015-03-31 14:46:10 Two-hybrid screening Strep-tag Mdm2 Multiprotein complex Hsp90 Membrane protein P21 Biology Proteins P53
56	Exosomes from Hepatitis C Infected Patients Transmit HCV Infection and Contain Replication Competent Viral RNA in Complex with Ago2-miR122-HSP90 Terence N. Bukong., Fatemeh Momen-Heravi., Karen Kodys, Shashi Bala, Gyongy Add to Reading List Source URL: www.altogen.com Language: English - Date: 2014-12-16 13:44:06 Organelles Hepatitis C virus Hepatitis MiR-122 Hepatitis C Plasmacytoid dendritic cell Hepatitis C and HIV co-infection Hepacivac Biology Genetics Exosome
57	doi:[removed]S0092[removed] Add to Reading List Source URL: hogness.stanford.edu Language: English - Date: 2012-04-11 13:48:41 Transcription factors Ecdysone receptor Hsp90 Steroid hormone receptor Hop Hsp70 Chaperone Ecdysone Nuclear receptor Biology Intracellular receptors Cell biology
58	# 3069 Heat Shock Protein 90 Inhibitor in Patients With Refractory Solid Tumors: A Phase I Pharmacokinetic And Pharmacodynamic Study Of AT13387 G I Shapiro1, E L Kwak2, B Dezube3, D P Lawrence2, J M Cleary1, S Lewis4, M Add to Reading List Source URL: astx.com Language: English Biology Hsp70 Hsp90 inhibitors Hsp90 Methadone Prostate cancer Heat shock proteins Chemistry Medicine
59	The HSP90 inhibitor, AT13387, demonstrates potent anti-tumor activity in both imatinib-sensitive and -resistant gastrointestinal stromal tumor models No A217 Tomoko Smyth1, Thomas Van Looy2, Jayne Curry1, Ana Rodriguez- Add to Reading List Source URL: astx.com Language: English Imatinib Piperazines Pyridines Pyrimidines Gastrointestinal stromal tumor CD117 Tyrosine kinase Sunitinib Hsp90 Biology Chemistry Organic chemistry
60	OPEN Citation: Cell Death and Disease[removed], e566; doi:[removed]cddis[removed] & 2013 Macmillan Publishers Limited All rights reserved[removed]www.nature.com/cddis Add to Reading List Source URL: www.nature.com Language: English - Date: 2013-03-28 10:56:47 Apoptosis Heat shock proteins Immune system Cancer research Hsp90 inhibitors Hsp90 Geldanamycin Bcl-2 family Caspase 3 Biology Cell biology Programmed cell death

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