Fragment-based lead discovery

Results: 10



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Continuing Professional Development Fragment-based lead discovery An introduction to the methods and applications A one day workshop that will provide an overview of current practise in fragment-based discovery methods.

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Source URL: www.ysbl.york.ac.uk

Language: English - Date: 2015-09-01 09:49:30
    2

    GE Healthcare Life Sciences 生技醫藥研發平台系列講座 BiacoreTM for fragment based lead discovery and for studies of membrane protein interactions

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    Source URL: bcf.assic.sinica.edu.tw

    Language: English - Date: 2011-10-03 04:53:56
      3Medicinal chemistry / Heat shock proteins / Clinical research / Hsp90 / Hsp70 / Drug design / Fragment-based lead discovery / Virtual screening / IC50 / Pharmaceutical sciences / Pharmacology / Drug discovery

      Fragment-Based Drug Design of AT13387 - A Novel and Efficacious Inhibitor of Hsp90. A.J. Woodhead , H. Angove, O. Callaghan, M. Carr, G. Chessari, M. Congreve, J. Cosme, S. Cowan, J. Coyle, P. Day, R. Downham, T. Early,

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      Source URL: astx.com

      Language: English - Date: 2012-12-13 18:06:00
      4Proteins / Heat shock proteins / Drug discovery / Clinical research / Hsp90 inhibitors / Hsp70 / Hsp90 / Fragment-based lead discovery / Chaperone / Pharmaceutical sciences / Pharmacology / Medicine

      Fragment-based Drug Discovery of the Synthetic Small Molecule HSP90 Inhibitor AT13387 A211 Christopher W. Murray, Maria G. Carr, Gianni Chessari, Miles Congreve, Joseph E. Coyle, Philip J. Day, Lynsey Fazal, Martyn Frede

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      Source URL: astx.com

      Language: English
      5Medicinal chemistry / Clinical research / Fragment-based lead discovery / Drug design / Hsp90 inhibitors / Astex / DNA-encoded chemical library / High-throughput screening / Pharmaceutical sciences / Drug discovery / Pharmacology

      Fragment-Based Drug Discovery: Technologies, Applications, and Pipelines Executive Summary  Executive Summary

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      Source URL: www.insightpharmareports.com

      Language: English - Date: 2012-04-16 09:21:38
      6Medicinal chemistry / Pharmacology / Drug discovery / Pharmaceutical industry / Clinical research / Assay / High-throughput screening / Drug discovery hit to lead / Pharmaceutical sciences / Chemistry / Science

      Domainex announces the expansion of its assay services and the launch of its unique fragment-based screening collection. Cambridge, UK, 6th January[removed]Domainex Ltd., the UK-based fully integrated drug discovery compan

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      Source URL: www.domainex.co.uk

      Language: English - Date: 2012-05-29 09:32:49
      7Pharmaceutical sciences / Molecular modelling / Bioinformatics / Medicinal chemistry / Computational chemistry / Virtual screening / Drug design / Fragment-based lead discovery / Docking / Chemistry / Science / Drug discovery

      Docking for fragment inhibitors of AmpC ␤-lactamase Denise G. Teotico1, Kerim Babaoglu1,2, Gabriel J. Rocklin, Rafaela S. Ferreira, Anthony M. Giannetti3, and Brian K. Shoichet4 Department of Pharmaceutical Chemistry,

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      Source URL: shoichetlab.compbio.ucsf.edu

      Language: English - Date: 2013-10-15 11:56:56
      8Drug discovery / Medicinal chemistry / Bioinformatics / Pharmacology / Computational chemistry / Virtual screening / Drug design / Fragment-based lead discovery / Beta-lactamase / Chemistry / Pharmaceutical sciences / Science

      ARTICLES Molecular docking and ligand specificity in fragment-based inhibitor discovery © 2009 Nature America, Inc. All rights reserved.

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      Source URL: shoichetlab.compbio.ucsf.edu

      Language: English - Date: 2013-10-15 11:56:55
      9Drug discovery / Clinical research / Tyrosine kinase receptors / Plexxikon / Protein kinase / Fragment-based lead discovery / AKT / CD135 / Tyrosine kinase / Pharmaceutical sciences / Pharmacology / Medicinal chemistry

      Automated Data Analysis in NMR Fragment Based Screening by ACD/Automation Server

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      Source URL: www.acdlabs.com

      Language: English - Date: 2012-05-01 07:16:17
      10Chemistry / Medicinal chemistry / Cheminformatics / Pharmacology / Bioinformatics / Fragment-based lead discovery / Chemical library / Library / High-throughput screening / Pharmaceutical sciences / Science / Drug discovery

      Fragment library design_Layout 1

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      Source URL: www.maybridge.com

      Language: English - Date: 2013-01-21 06:32:45
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