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Tumor suppressor genes / Carcinogenesis / Proteins / Genetics / Apoptosis / P53 / Caretaker gene / P16 / Ataxia telangiectasia / Medicine / Biology / Oncology


REVIEWS Genomic instability — an evolving hallmark of cancer Simona Negrini*, Vassilis G. Gorgoulis‡ and Thanos D. Halazonetis*§
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Document Date: 2011-06-08 05:03:15


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City

Geneva / Walsh / Athens / Denko / /

Company

Macmillan Publishers Limited. / TA B I LE IW TY EV S a / /

Country

Switzerland / United States / Greece / /

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Event

Product Issues / /

Facility

Virchows Arch / University of Geneva / University of Athens / The checkpoint / /

IndustryTerm

experimental systems / protein product / cancer therapy / fragile site / ONLINE PDF / p16INK4A protein product / protein homeostatic machinery / oncogene product / /

MedicalCondition

ataxia telangiectasia / pancreatic adenocarcinomas / human glioblastoma genes / J. Tumor / human glioblastoma multiforme / rare autosomal recessive disease / pediatric cancer / hereditary non-polyposis colon cancer / Bloom syndrome helicase / sporadic human cancers / retinoblastoma / colorectal cancer / B. Breast cancer / metastasis / human disorders / Werner syndrome / pancreatic adenocarcinomas TP53 CDKN2A Tumours Wild-type / human cancers / colorectal cancers / autosomal dominant disease / colon cancer / hereditary nonpolyposis colon cancer / xeroderma pigmentosum / solid and haematopoietic cancers / CIN / human cancers BUB1 / early passage cancer / above / hereditary cancers / each cancer / untreated sporadic human cancers / untreated glioblastoma / hereditary cancers / human pancreatic cancers / inherited cancers / multistage carcinogenesis / lung adenocarcinoma / breast cancer / treated glioblastomas / Nijmegen breakage syndrome / sporadic cancer / glioblastoma / breast carcinoma / lung adenocarcinoma studies / cancers / untreated lung carcinomas / additional colon cancers / colon carcinoma / tumor / breast cancers / INK4a tumor / cancer / J. E. Cancer / primary cancers / primary tumours / primary brain cancer / untreated glioblastomas / glioblastomas / human cancer / Telomere dysfunction / contraction / sporadic cancers / tumour / epithelial cancers / pancreatic cancers / neurofibromatosis / breast and ovarian cancer / p53 tumor / lung cancer / HNPCC / hereditary nonpolyposis colorectal cancer / related disorders / lung adenocarcinomas / xeroderma pigmentosum group B-complementing protein / specific cancer / Cockayne syndrome / early passage human colon cancer / carcinomas / Werner syndrome helicase / Lynch syndrome / colorectal tumors / autosomal recessive disease / tumours / /

MedicalTreatment

counselling / cancer therapy / /

Movie

W. V / /

OperatingSystem

XP / /

Organization

University of Geneva / School of Medicine / Department of Biochemistry / Department of Molecular Biology / Department of Histology and Embryology / Swiss National Science Foundation / University of Athens / /

Person

Simona Negrini / J. M. Transient / Zambetti / Gustav Fischer Verlag / Olson / JO JODSFBTFE / /

Position

oncogene-induced DNA replication stress model for cancer development / genetic model for colorectal tumorigenesis / DNA damage model for cancer development / T. D. / Bishop / G. P. / /

Product

D.H. e / base / /

ProvinceOrState

W. V. / North Carolina / /

PublishedMedium

Molecular Biology / /

Technology

Genomics / gene amplification / X-ray / ATM / apoptosis / single nucleotide polymorphism / treating cancer / recombination / /

URL

www.molbio.unige.ch / http /

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