Bromodomain

Results: 11



#Item
1

Therapeutic targeting of the p300/CBP bromodomain for the treatment of castration resistant prostate cancer Nigel Brooks1, Neil Pegg1, Jenny Worthington2, Barbara Young3 and Amy Prosser3 1CellCentric Ltd, Chesterford Res

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Source URL: www.cellcentric.com

Language: English - Date: 2017-12-21 05:45:15
    2

    Article pubs.acs.org/jmc Fragment-Based Design of Selective Nanomolar Ligands of the CREBBP Bromodomain Andrea Unzue,† Min Xu,‡ Jing Dong,‡ Lars Wiedmer,‡ Dimitrios Spiliotopoulos,‡ Amedeo Caflisch,*,‡

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    Source URL: www.biochem-caflisch.uzh.ch

    - Date: 2015-08-27 04:54:08
      3Biology / Genetics / Protein structure / Epigenetics / Proteins / Protein domains / Molecular biology / Bromodomain / Organic reactions / BRD4 / Histone / Nucleosome

      DOI: cmdcMinireviews Binding Mode of Acetylated Histones to Bromodomains: Variations on a Common Motif

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      Source URL: www.biochem-caflisch.uzh.ch

      Language: English - Date: 2015-08-27 04:54:08
      4Proteins / Epigenetics / Organic reactions / Posttranslational modification / Bromodomain / Acetylation / Histone / BRD4

      “Targeting gene expression by direct inhibition of bromodomain-acetyl-lysine readout” This seminar will summarize our efforts to develop selective inhibitors targeting bromo and extra terminal (BET) bromodomains, lea

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      Source URL: wpi-iiis.tsukuba.ac.jp

      Language: English - Date: 2015-12-17 00:35:56
      5

            REACTION  BIOLOGY  RECEIVES  NIH  GRANT  AWARD  FOR  BROMODOMAIN  RESEARCH     Malvern  PA,  June  11,  2015-­‐-­‐Reaction  Biology  Corporation  (

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      Source URL: www.reactionbiology.com

      Language: English - Date: 2015-06-11 15:08:29
        6

        Quality Data. Quality Support. Towards comprehensive coverage of Bromodomain family for drug screening and discovery Epigenetic regulation of gene expression is a highly dynamic and

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        Source URL: www.reactionbiology.com

        Language: English - Date: 2014-07-24 10:10:30
          7Epigenetics / Protein domains / Organic reactions / Posttranslational modification / Bromodomain / Histone / Gene expression / Acetylation / Biology / Proteins / Chemistry

          “Targeting gene expression by direct inhibition of bromodomain-acetyl-lysine readout” This seminar will summarize our efforts to develop selective inhibitors targeting bromo and extra terminal (BET) bromodomains, lea

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          Source URL: www.tsukuba.ac.jp

          Language: English - Date: 2015-01-18 23:33:47
          8Epigenetics / Protein domains / Organic reactions / Posttranslational modification / Bromodomain / Histone / Gene expression / Acetylation / Biology / Proteins / Chemistry

          “Targeting gene expression by direct inhibition of bromodomain-acetyl-lysine readout” This seminar will summarize our efforts to develop selective inhibitors targeting bromo and extra terminal (BET) bromodomains, lea

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          Source URL: wpi-iiis.tsukuba.ac.jp

          Language: English - Date: 2015-01-15 04:14:13
          9Gene expression / RNA / Transcription factors / NFE2L2 / KEAP1 / BRD4 / Papillomaviridae / Epigenetics / RNA interference / Biology / Genetics / Biochemistry

          The bromodomain protein BRD4 regulates the KEAP1/NRF2-dependent oxidative stress response

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          Source URL: www.nature.com

          Language: English - Date: 2014-04-24 08:56:35
          10Facit

          Fluorinov  Pharma  and  FACIT  Announce  Investment  in   Breakthrough  Bromodomain  Inhibitors  for  the     Treatment  of  Cancers   TORONTO,  ON  (January  07,

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          Source URL: oicr.on.ca

          Language: English - Date: 2015-01-07 13:10:39
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