Proc Natl Acad Sci U S A / Hess / HP / Swick AG / Stephens / /
Country
Germany / Canada / / /
Event
Product Issues / /
Facility
University of British Columbia / University of Giessen / University of Wuerzburg / /
IndustryTerm
obese gene product / energy / food intake-dependent / food intake / energy expenditure acting / /
MedicalCondition
hyperinsulinemia and manifest type / hyperinsulinemia / JE / severe insulin resistance / insulinoma cells / both insulin resistance / obesity / rat insulinoma cell line CRI-G1 / hyperleptinemia and adipogenic diabetes / MS / adipogenic diabetes mellitus / leukemia / Insulin deficiency / insulin resistance / leptin DIABETES / disease / obesity-induced insulin resistance / adipose tissue DIABETES / hyperglycemia / chronic hypersecretion / diabetes / metabolic syndrome / Chronic effects / diabetes mellitus / NIDDM / inflammation / initial hyperinsulinemia / S156 DIABETES / /
MedicalTreatment
gene therapy / /
NaturalFeature
ob/ob islets / KATP channel / /
Organization
Division of Metabolism / Endocrinology / and Molecular Medicine / University of Giessen / Division of Metabolism / University of British Columbia / Vancouver / Islet Transplant Center / American Diabetes Association / US Federal Reserve / University of Wuerzburg / Leptin administration / /
Person
Arch Physiol Biochem / Exp Biol Med / T.J. Kieffer / Jochen Seufert / Scott V / R. Bretzel / /
Leptin Effects on Pancreatic -Cell Gene Expression and Function Jochen Seufert The hormone leptin is secreted from white adipocytes, and serum levels of leptin correlate with adipose tissue