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Euglenozoa / Antiprotozoal agents / Hydrazones / Nifurtimox / Sulfones / Chagas disease / Trypanosoma cruzi / Enantiomer / Racemic mixture / Chemistry / Organic chemistry / Stereochemistry


Enantiomers of Nifurtimox Do Not Exhibit Stereoselective AntiTrypanosoma cruzi Activity, Toxicity, or Pharmacokinetic Properties Carolina B. Moraes,a* Karen L. White,b Stéphanie Braillard,c Catherine Perez,d Junghyun Go
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Document Date: 2015-05-19 10:57:38

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City

Geneva / Shanghai / Perth / Campinas / Victoria / Suzhou / Parkville / /

Company

Swiss Agency for Development / WuXi AppTec Co. Ltd. / WuXi AppTec Ltd. / Epichem Pty. Ltd. / Charman SA. / Ames / /

Country

Switzerland / Germany / Netherlands / Brazil / Australia / United Kingdom / China / /

Currency

pence / /

/

Facility

Monash Institute of Pharmaceutical Sciences Animal Ethics Committee / Monash University / Murdoch University / /

IndustryTerm

nifurtimox racemate / treatment of Chagas disease / /

MedicalCondition

acute Chagas disease / strain / parasitemia / Chagas disease / chronic stage / Neglected Diseases / infection / /

MedicalTreatment

chemotherapy / immunosuppression / catheter / /

Organization

Korean Government / Swiss Agency for Development and Cooperation / Monash Institute / Instituto de Biologia Molecular Celular / American Society for Microbiology / i.v. administration / National Research Foundation of Korea / Monash University / Doctors without Borders / Department for International Development / Animal Ethics Committee / Centre for Drug Candidate Optimisation / DNDi / Murdoch University / Universidade do Porto / Porto / Reconstruction Credit Institution-Federal Ministry of Education / Eric Chatelainc Center for Neglected Diseases Drug Discovery / /

Person

C. Andrew Thompson / Carolina B. Moraes / Optimisation / Lucio Freitas-Junior / Catherine Perez / David M. Shackleford / Susan A. Charman / Karen L. White / Eric Chatelain / /

Position

Directorate General for International Cooperation / Gazzinelli RT / /

Product

cyclophosphamide / isoflurane / /

ProvinceOrState

Washington / /

PublishedMedium

Antimicrobial Agents and Chemotherapy / /

RadioStation

Araujo-Junior AM / /

Technology

X-ray / Drug Discovery / Chemotherapy / http / /

URL

http /

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