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Mechanosensitive channels / Cell membrane / Membrane protein / Spheroplast / Ion channel / Surface tension / Elasticity of cell membranes / Biology / Membrane biology / Hydrophobic mismatch


Analytic models for mechanotransduction: Gating a mechanosensitive channel Paul Wiggins* and Rob Phillips†‡ Divisions of *Physics, Mathematics, and Astronomy and †Engineering and Applied Science, California Institu
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Document Date: 2005-11-27 14:18:08


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City

Mesquita / Pasadena / New York / London / /

Company

Dan / N. & Safran / S. A. / Blount / /

Country

United States / /

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Facility

California Institute of Technology / /

IndustryTerm

thickness deformation energy / thickness deformation free energy / induced bilayer deformation energy / free energy / protein conformational energy / free-energy differences / free energy difference / conformational energy / deformation energy / energy density / schematic protein energy / protein energy / energy minima / protein conformation energy / deformation energy arising / bilayer deformation energy / energy / bilayer deformation free energy / mechanosensitive systems / free-energy difference / simplified free-energy function / deformation free energy / conformational energy barrier / bilayer deformation energy change / conformational energy landscape / energy budget scales / conformational free energy / interface energy / bilayer deformation energy landscape / free-energy contribution / minimum energy state / empirical rate law / open and closed state protein conformation energy / free-energy minima / lowest free energy / /

Organization

California Institute of Technology / Keck Foundation / National Science Foundation / Center for Integrative Multiscale Modeling and Simulation / National Academy of Sciences / /

Person

Klaus Schulten / Nat / Tom Powers / Physiol / Ben Freund / Olaf Andersen / Sergei Sukharev / Paul Wiggins / Doug Rees / Eduardo Perozo / Evan Evans / Schroeder / Rob Phillips / Douglas C. Rees / /

Position

Walker / General / detailed model of channel gating / simple / self-consistent model for channel– membrane interaction / /

Product

LG PC12 Radio / /

ProgrammingLanguage

RC / LPC / /

ProvinceOrState

New York / O. N. / California / /

Region

East California / /

Technology

x-ray / SDSL / spectroscopy / Simulation / /

URL

www.pnas.org兾cgi兾doi兾10.1073兾pnas.0307804101 / /

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