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Fibroblast growth factor / Tyrosine kinase / Protein kinase inhibitor / Protein kinase / IC50 / Receptor tyrosine kinase / Tyrosine kinase receptors / Biology / Cell biology


Development of Inhibitors of the Fibroblast Growth Factor Receptor (FGFR) Kinase Using a Fragment Based Approach Poster: 3626 M S Squires, T Perera$, G Saxty, C W Murray, P King$, G A Ward, R Feltell, S Rich, P Angibaud$
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City

Newcastle upon Tyne / Cambridge / Washington / Beerse / /

Company

Novartis / Astex Therapeutics Limited. / AstraZeneca / N T Thompson Astex Therapeutics Ltd / /

Country

Belgium / United Kingdom / /

Facility

Paul O’Gorman Building / Northern Institute / /

MedicalCondition

Gastric Cancer / cancer / Multiple myeloma / disease / Bladder Cancer / tumour / carcinoma / FGFR-dependent tumours / Endometrial Cancer / multiple myeloma xenografts KMS11 / prostate cancer / MS / breast cancer / tumours / /

Organization

Northern Institute for Cancer Research / /

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Position

King / Representative / /

PublishedMedium

Cancer Research / /

Technology

drug discovery / X-ray / Pharmacodynamics / Apoptosis / /

URL

www.astex-therapeutics.com / /

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