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Hematologic neoplasms / Protein domains / Fibroblast growth factor / Morphogens / Multiple myeloma / Biology / Tyrosine kinase receptors / Cell biology


Development of Inhibitors of the Fibroblast Growth Factor Receptor (FGFR) Kinase Using a Fragment Based Approach[removed]M S Squires, G Saxty, C W Murray, V Berdini, G A Ward, M Batey*, A Peasland*,D Miller, S J Rich, A C
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Document Date: 2012-12-13 18:06:00


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File Size: 379,81 KB

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City

Newcastle upon Tyne / San Diego / Cambridge / /

Company

Astex Therapeutics Ltd. / /

Country

United Kingdom / /

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Facility

A Pike / Northern Institute / Paul O’Gorman Building / /

IndustryTerm

in vitro systems / serum free media / /

MedicalCondition

NOD/SCID / Ba/F3-TEL/FGFR3 Xenograft tumours / ve Multiple Myeloma / TEL/FGFR3 Murine B-cell Tumours / cancer / Multiple Myeloma / disease / KMS11 Xenograft tumours / positive multiple myeloma line / In KMS11 tumours / MS / FGFR3 positive multiple myeloma models / +ve Multiple Myeloma / positive Multiple Myeloma / Tumour / tumours / /

Organization

Northern Institute for Cancer Research / /

Person

Murray / V / /

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PublishedMedium

Cancer Research / /

Technology

X-Ray / Apoptosis / /

SocialTag