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City Santa Clara / Houston / Madison / La Jolla / Cambridge / / Company Millipore / GraphPad Software Inc. / Molecular Biology Inc. / Noscira S.A. / GE Healthcare / PerkinElmer / Corning / / Country United Kingdom / Spain / Denmark / / / Event FDA Phase / / Facility I complex / To shed / E-I complex / Invitrogen European Screening Center / / / IndustryTerm active site / immobilized metal ion affinity chromatography / potent pharmacological tool / treatment of Alzheimer disease / non-selective chemical modification / adenomatous polyposis coli gene product / chemical structure / centrifugal filter devices / / MedicalCondition adenomatous polyposis coli / dementia / dysfunction / slow dissociation / infectious recombinant baculovirus particles / disorder / synaptic dysfunction / dissociation / tauopathies / disease / progressive supranuclear palsy / infection / Alzheimer disease / inflammation / / Organization European Screening Center / Medicinal Chemistry Department / European Commission / European Union / American Society for Biochemistry / / Person María del Monte-Millán / Ana Fuertes / Min / Miguel Medina / Elena Delgado / Juan Manuel Domínguez / Max / María del Monte-Milla / / / Position mediator / relevant player / player / Major / representative / / Product pseudo / trimethoprim / acyclovir / guanidine hydrochloride / allopurinol / GSK-3 / / ProgrammingLanguage C / / ProvinceOrState Alabama / South Dakota / / PublishedMedium Molecular Biology / / Technology bioinformatics / electrophoresis / directed mutagenesis / apoptosis / time-resolved FRET-based LanthaScreenTM technology / drug discovery / LYTETM technology / measured using the time-resolved FRET-based LanthaScreenTM technology / / URL http /
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Enzymology: Evidence for Irreversible Inhibition of Glycogen Synthase Kinase-3 β by