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Carcinogenesis / Cell cycle / Spindle checkpoint / CDK inhibitor / Tyrosine kinase / Medicine / Biology / Protein kinase inhibitors


DOI:.CANChromosomal Instability Confers Intrinsic Multidrug Resistance Alvin J.X. Lee, David Endesfelder, Andrew J. Rowan, et al. Cancer Res 2011;71:Published online March 1, 2011.
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Document Date: 2012-03-21 14:33:16


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City

MNK1 Inhibitor / Lincoln / /

Company

Translational Cancer Therapeutics Laboratory / Stata Corp / EMD Biosciences / HCT116 MAD2þ / Signal Transduction Laboratory / Affymetrix / 1Translational Cancer Therapeutics Laboratory / CIN / Pearson / performed using Stata / 3High Throughput Screening Laboratory / /

Country

United Kingdom / /

Currency

CRC / /

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Event

Product Recall / Product Issues / /

Facility

Hospital Informatics Program / Wellcome Trust Sanger Institute / Cancer Research UK London Research Institute / Inn Fields / Technical University of Denmark / Royal Marsden Hospital / Calbiochem Kinase Inhibitor Library / /

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IndustryTerm

Cancer Therapeutics / cell line systems / /

MarketIndex

Genome Integrity / /

MedicalCondition

CIN cancer / Integral Copy Numbers In Cancer / Introduction Colorectal cancer / colorectal cancer / tumor DNA / solid tumors / charles.swanton@cancer / CINþ cancer / CINþ tumor / late-stage disease / CIN colorectal cancer / karyotypically complex cancer / diploid cancers / tumor / activated KRASinitiated mouse lung tumor / Cancer / tumors / distinct tumor / colorectal and other solid tumors / tumor CIN / CIN parental cancer / increased tumor / deficiency / /

MedicalTreatment

adjuvant therapy / /

Organization

Harvard Medical School / Technical University of Denmark / Wellcome Trust Sanger Institute / Harvard / Royal Marsden Hospital / Department of Medicine / Wellcome Trust Centre for Human Genetics / Cancer Research UK London Research Institute / American Association for Cancer Research / MIT Division of Health Sciences and Technology / AACR Publications Department / /

Person

David Endesfelder / Aurora Kinase Inhibitor II / Andrew J. Rowan / Aurora Kinase Inhibitor III / Aurora Kinase / /

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Position

Corresponding Author / Fisher / representative / /

Product

Carboplatin / KRAS oncogenic stimulus / Thioguanine / M14 / Mercaptopurine / Podofilox / Mitomycin / Tamoxifen Citrate / Etoposide / Floxuridine / Vinblastine Sulfate / Doxorubicin Hydrochloride / Azathioprine / Fluorouracil / Daunorubicin Hydrochloride / Chloramphenicol / Mitoxantrone / cytokinesis / sister chromatid cohesion / /

PublishedMedium

Cancer Research / /

Technology

ATM / html / SNP / recombination / /

URL

http /

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