Seattle / Cambridge / Gainesville / Riverside / Bethesda / La Jolla / Reno / San Diego / /
Company
Genetic Therapy Inc. / Gene Medicine Inc. / Chiron Corporation / Human Genome Sciences Inc. / Capital Consulting Corporation / Syndrome Association Inc. / Ariad Pharmaceuticals Inc. / Transgene Inc. / American Homecare Federation Inc. / Muscular Dystrophy Association Inc. / Booz-Allen & Hamilton Inc. / Osiris Therapeutics Inc. / Cell Genesys Inc. / Canji Inc. / Rhone-Poulenc Rorer / Systemix Inc. / Merck / I. Risk Group / Targeted Genetics Corporation / Introgen Therapeutics Inc. / Ambience Awareness International Inc. / Genzyme Corporation / Vical Inc. / Schering Plough Corporation / Glaxo Wellcome Inc. / Bayer Corporation / /
Event
Product Issues / FDA Phase / Product Recall / /
Facility
Chapel Hill Page / University of Florida Martha French / Albert Einstein College of Medicine M. Louise Markert / University of Florida / University of Southern California Valder Arruda / Hospital Dale G. Ando / University of California / University of Pennsylvania Medical Center Alan McClelland / Hospital Elizabeth A. Austin / Children’s Hospital of Philadelphia Christine-Lise Julou / University of North Carolina Warren W. Nichols / University of Pennsylvania Debbie Lavinge / Veterans Hospital / University of Alabama / Salk Institute / Rockville Pike / University of Pennsylvania Margaret Liu / University of North Carolina / University of Pennsylvania Medical Center Antoine Yver / University of Minnesota Claudia A. Mickelson / University of Pennsylvania Medical Center Nelson Wivel / University School / University of Pennsylvania Annie Kennedy / University of Pennsylvania Medical Center Deborah Hurst / University of Southern California / Indiana University / Children ’s Hospital of Philadelphia Ayse Hisim / Massachusetts Institute of Technology Ad Hoc Consultants / /
IndustryTerm
therapy protocols / treatment for some hereditary and acquired diseases / telephone conference calls / nontherapeutic protocols / plasmid systems / transfer protocol / injection site / transfer protocols / electronic discussion / /
MedicalCondition
HIV / murine leukemia / recurrent squamous cell carcinoma / diseases / infection / disorders / disease / Severe Hemophilia B / pain / IX Deficiency / monogenic diseases / hemophilia A / cancer / Guillain-Barre acute syndrome / mostly cystic fibrosis / Canavan disease / hereditary and acquired diseases / metastatic melanoma / beta-Thalassemia / cystic fibrosis / hemophilia B / /
MedicalTreatment
antibiotics / counseling / gene therapy / /
Organization
University of California / office of Recombinant DNA Activities / Rockville / Stanford University School of Medicine Haig Kazazian / Massachusetts Institute of Technology / University of Pennsylvania Medical Center / FDA / University of Southern California Valder Arruda / Food and Drug Administration / University of Pennsylvania / Office for Protection / Indiana University / Indianapolis / Veterans Hospital / Mount Sinai School of Medicine Jay J. Greenblatt / Salk Institute / Inc. Arifa Khan / Texas Children’s Hospital / Southern Illinois University School of Medicine / DEPARTMENT OF HEALTH AND HUMAN SERVICES / American Homecare Federation / Association of American Medical Colleges Siyamak Rasty / National Medical Research Institute / Duke University / Albert Einstein College of Medicine / University of Alabama at Birmingham / University of California / Riverside / National Institute of Health / Muscular Dystrophy Association / University of North Carolina / University of Southern California / Los Angeles / National Endowment for the Humanities / Massachusetts General Hospital / Recombinant DNA Advisory Committee / Council for Responsible Genetics / Joshua M. Gordon SMA Foundation / Naval Medical Research Center / Syndrome Association / Cystic Fibrosis Foundation / Institute of Technology Ad Hoc Consultants / University of Florida / Cornell University Medical College / University of Minnesota / Joshua M. Gordon Foundation / /
Person
Terry Galvin / Suzanne L. Epstein / Owens Closing / James E. Morris / Dale G. Ando / Chipper Whalen / Sonia Skarlatos / Andrew Quon / Jay Siegel / Edward Otto / Lin Fei / Robert L. Clark / Becky Lawson / Nancy M.P. King / R. Michael Blaese / James Albright / Robert Anderson / Pia Delaire / Gary J. Kurtzman / Ruth Macklin / Stephen M. Kaminsky / Michael C. Scaife / Steve Bauer / Daniel P. Jones / Ross Durland / Claudia Mickelson / Paul R. Billings / Mark A. Kay / David A. Gordon / Philip Noguchi / Samuel C. Wadsworth / Donald Gay / Joyce Frey / Jean-Sylvain Demelier / Roland Owens / Linda Couto / Dominick Vacante / David E. Colburn / Tim Hefferon / Katherine A. High / Jeffrey Friedman / Mitchell Goldman / Christine Boisclair / Markert Requester / Martha Leibbrandt / Margaret M. Dillon / Stephanie L. Simek / Lou Zumstein / Alex La Croix / Helen Liu / Will Lee / Thomas Shih / W. French Anderson / Stephen L. Hoffman / Debra Dotson / Barry Polenz / Terence R. Flotte / Diane Stothard / Debra W. Knorr / Patricia L. Novak / Louise T. Chow / Judith A. St. George / Thomas C. Reynolds / Barry Bowman / Robert J. Beall / William K. McVicar / Nancy Herring / Lana Skirboll / Haig H. Kazazian / Jr. / Christine-Lise Julou / Dale E. Johnson / Mike Miller / Anne Dunne / Philip Scuderi / Jon A. Norman / James Kaiser / Dave Gordon / Peter Larson / Judith S. Greengard / Margaret Lavinge / Margarita C. Curras-Collazo / Gerard Spahn / Theresa Pierson-Sunding / R. Scott McIvor / Jennifer Kostiuk / Catherine Manno / Jim Lavinge / John D. Iuliucci / Lonnie Russell / Richard O. Snyder / Holger H. Roehl / David Kaslow / Jon W. Gordon / Wanda deVlaminck / Joseph Hughes / Jay J. Greenblatt / Tina M. Grasso / Kathryn A. Miller / Marion Valerio / Audrey Chang / Jan Casadei / Carlo Russo / Thomas E. Hogan / Lorna Speid / Dan Takefman / Mickelson Requester / James Wilson / Valerie McDonnell / Roland A. Owens / Gene Rosenthal / Rebecca Link / Christine M. Pannunzio / Brenda Wong / Margaret Liu / Bette Goldman / Roland Herzog / Joshua M. Gordon / Angus Grant / Esmail Zanjani / Donna R. Savage / M. Louise Markert / Rebecca Spicler / Owens Closing Remarks / / /
Position
Investigator / NIDDK / investigator / President / King / Executive Secretary / chair of each working group / working group chair / independent counselor / Director / Biological Safety Officer / Chair / /
DEPARTMENT OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH RECOMBINANT DNA ADVISORY COMMITTEE MINUTES OF MEETING March 11-12, 1999 TABLE OF CONTENTS