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Immunology / Immune system / Biotechnology / Virus-like particle / Monoclonal antibodies / Epstein–Barr virus / Fusion protein / Antibody / Infectious mononucleosis / Biology / Anatomy / Viral diseases


A chimeric EBV gp350/220-based VLP replicates the virion B-cell attachment mechanism and elicits long-lasting neutralizing antibodies in mice
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City

Worcester / Boston / Bradford / EBV / San Diego / Newcastle / /

Company

IgG / Immunization / Hamamatsu Orca AG / Tree Star Inc / Olympus / Millipore / GraphPad Software Inc. / Life Science Technologies / Graph Pad Prism 6 Software / Creative Commons / Jackson Laboratories / Life Sciences Technologies / analyzed using Graph Pad Prism 6 Software / /

Country

United States / /

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Event

FDA Phase / /

Facility

Northwestern University / University of Massachusetts Medical School IACUC / University of Massachusetts Medical School / /

IndustryTerm

attachment site / chemical induction / restriction enzyme site / /

MedicalCondition

vaccines targeting hepatitis B / sarcoma herpesvirus / HIV / lymphoma / post-transplant lymphoproliferative disorders / high income countries primary infection / HIV-associated B-cell lymphomas / clinical disease / novel Newcastle disease virus / human erythroleukemia / Burkitt’s lymphoma / illness / Raji cell infection assay / certain gastric and sporadic carcinomas / nasopharyngeal carcinoma / disease / primary EBV infection / malaria / block infection / acute infectious mononucleosis / Hodgkin lymphoma / associated tumors / latent infection / systemic inflammation / infection / neonatal infection / splenic rupture / syndrome / /

MedicalTreatment

immunization / immunizations / vaccination / booster immunizations / immunosuppression / vaccinations / /

Organization

SUNY Upstate Medical School / Federal Drug Agency / Northwestern University / Chicago / Department of Medicine / Beth Israel Deaconess Medical Center/Harvard Medical School / University of Massachusetts Medical School IACUC and Institutional Biosafety Committee / University of Massachusetts Medical School / /

Person

Liisa Selin / Christine King / Javier Gordon / Reverse Primer / Richard Longnecker / /

Position

candidate for development / RT / author / candidate for prophylactic subunit vaccine development / Forward / /

Product

penicillin / Federal Drug / /

ProvinceOrState

Connecticut / Massachusetts / /

TVStation

KSHV / /

Technology

antibodies / ATG / DNA sequencing / /

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http /

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