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Apoptosis / Programmed cell death / Hsp27 / Phosphoinositide 3-kinase / Alpha crystallin / Apoptosome / AKT / PI3K/AKT/mTOR pathway / Lens / Biology / Cell biology / Proteins


The anti-apoptotic function of human αA-crystallin is directly related to its chaperone activity
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Document Date: 2010-03-18 06:52:31


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City

Ann Arbor / Valencia / New York / Salt Lake City / Sunnyvale / Columbus / San Diego / Santa Cruz / /

Company

Echelon Biosciences / R21A / Qiagen / Visual Sciences / alphaA2 / Creative Commons / Bio-Rad / Macmillan Publishers Limited / /

Country

United States / /

Currency

pence / /

/

Event

FDA Phase / /

Facility

Case Western Reserve University / terminal FLAG / The Ohio State University / /

IndustryTerm

chemical-induced apoptosis / chemical modification / metabolic product / chemicals / /

MedicalCondition

human and experimental cataracts / breast carcinomas / tumor / autosomal dominant cataracts / cancer / Disease / age-related cataracts / tumor necrosis / diseases / /

MedicalTreatment

AID / /

Organization

National Institute of Health / Case Western Reserve University / Cleveland / National Science Foundation / The Ohio State University / Columbus / Prevent Blindness / Department of Ophthalmology and Visual Sciences / Ohio Lions Eye Research Foundation / /

Person

Bano Antiapoptotic / /

/

Position

original author / Senior Scientific Investigator / USA *Corresponding author / Fisher / /

Product

etoposide / B52 / HeLa / dimethyl sulfoxide / R49A / PI3K / /

ProvinceOrState

Ohio / South Dakota / /

Technology

alpha / antibodies / Biotechnology / directed mutagenesis / Cloning / Cell Signaling / apoptosis / /

URL

www.nature.com/cddis / /

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