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Signal transduction / Growth factors / Protein kinases / Cell signaling / AKT / Phosphoinositide 3-kinase / PI3K/AKT/mTOR pathway / Neurotoxicity / Neuroprotection / Biology / Cell biology / Biochemistry


OPEN Citation: Cell Death and Disease[removed], e1391; doi:[removed]cddis[removed] & 2014 Macmillan Publishers Limited All rights reserved[removed]www.nature.com/cddis
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Document Date: 2014-08-28 08:36:19


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File Size: 2,75 MB

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City

Frankfurt am Main / Paris / Kaiserslautern / SH / /

Company

PP PP sA sA / AP LP / FCS sAPP 20 PP sA / nM nM 25 10 nM 0 co / nM E1 E1 nM 50 nM 25 co / nM nM nM 50 25 0 co / SH-SY5Y APLP2-KD sA / ro co / nM nM nM 50 25 co / nM sA PP / PK sA / E1 nM nM 50 25 nM 0 co / B27 sA / IG sA / nM 50 nM nM 25 50 0 co / IG F1 PP sA / APP APP-KD sAPP co / PP nM sA / KD sA sA / PP sA / nM sA sA / nM co / kD E1 E1 nM nM 50 25 co / E1 sA PP PP / PP PP SH-SY5Y APP-KD sA / F1 20 nM IG sA PP / nM nM 25 10 0 co / Macmillan Publishers Limited / /

Country

Germany / France / /

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Event

Product Recall / Product Issues / /

Facility

shed Cell Death / Technical University / terminal MEFs MEF APP KO / Heidelberg University / stable SH-SY5Y APLP1 / Mainz University / Scale bar / Goethe University Hospital / Frankfurt University Hospital / Institute of Pharmacy / University Medical Center / terminal domain43 / 44 / /

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IndustryTerm

antiamyloidogenic processing / /

MedicalCondition

brain injury / Alzheimer’s disease / APP-depleted neuroblastoma cells / Disease / pertussis / pertussis toxin / neuroblastoma cells / KD SH-SY5Y neuroblastoma cells / /

Organization

PP sAPP / University Medical Center / KD sAPP / Technical University / Goethe University Hospital / kD APP / Institute of Pharmacy and Molecular Biotechnology / APP sAPP / Heidelberg University / Paul-Ehrlich-Institut / Frankfurt University Hospital / Mainz University / sAPP APP / AP sAPP / /

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Position

Representative / Germany *Corresponding author / /

Product

factor/ glucose / pGSK3beta 46 kD GSK3beta 46 / factor / serum / wth serum / serum/glucose / nM 50 nM 0 0 / dimethyl sulfoxide / background / mice / neurons / cells / /

Technology

Bioinformatics / antibodies / Biotechnology / apoptosis / Gene Therapy / Functional Genomics / Neurosurgery / genotype / /

URL

www.nature.com/cddis / /

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