| Document Date: 2014-05-05 14:05:15
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Company TIN2 Ab / Elsevier Inc. / myc Ab / / / Event Natural Disaster / Product Issues / / Facility TPP1/POT1 complex / The Rockefeller University / duplex DNA / TRF2 complex / terminus of TPP1 / TIN2/TRF1/TRF2 complex / TPP1/POT1a complex / / IndustryTerm telomere fusion products / distal site / / MedicalCondition ataxia telangiectasia / Dyskeratosis congenita / TPP1 deficiency / ORF / HTC75 tumor / dissociation / telomere dysfunction / POT1b Deficiency A / / Organization IF (red) / Rockefeller University / / Person Kaori K. Takai / / / Position model for RPA exclusion by TPP1/POT1 / / Product TIN2-Tethered POT1 / TPP1 / P-Chk2 Chk2 / MEFs / Cells POT1a/b DKO cells / cells / cells Molecular Cell / / Technology previous telomeric ChIP / hybridization / ATM / genotyping / DNA binding / DNA synthesis / DNA Chip / gene targeting / recombination / gel electrophoresis / /
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Molecular Cell Article Telomere Protection by TPP1/POT1 Requires Tethering to TIN2 Kaori K. Takai,1 Tatsuya Kibe,1,2 Jill R. Donigian,1,2 David Frescas,1 and Titia de Lange1,*