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Biotechnology / Emerging technologies / Tissues / Dysferlin / Myosatellite cell / Stem cell / Mesoangioblast / Skeletal striated muscle / Muscle / Biology / Muscular dystrophy / Muscular system


Partial dysferlin reconstitution by adult murine mesoangioblasts is sufficient for full functional recovery in a murine model of dysferlinopathy
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Document Date: 2010-08-05 05:58:10

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Crumlin / Madrid / Iowa City / Milano / Wetzlar / Columbus / Hamlet / Milan / Verviers / Paisley / San Jose / St. Louis / Santa Cruz / Poole / Barcelona / Raleigh / Newcastle upon Tyne / London / San Diego / /

Company

Hybridoma Bank / Leica Microsystems GmbH / ID Laboratories / Brodsky / Becton Dickinson Biosciences / Covance / MHC / La Rocca SA / Randox Laboratories / Ge / Engel AG / 5Stem Cell Laboratory / Macmillan Publishers Limited / /

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Canada / United Kingdom / Germany / Italy / Belgium / United States / Spain / /

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FDA Phase / Product Issues / /

Facility

National Institute of Health / San Raffaele Scientific Institute / University of Milan / Hospital Santa Creu / /

IndustryTerm

exercise training protocol / intracellular oil-red-positive vesicles / imaging / bona fide satellite cells / nuclei expressing myosin heavy chain / myosin heavy chain / injection site / cell therapy protocol / satellite cells / Satellite cell cultures / Exercise protocols / /

MedicalCondition

myopathy / a-sarcoglycan deficiency / untreated SCID / dysferlin-deficient muscular dystrophy / consequent inflammation / transplanted SCID / dystrophic untreated SCID / Distal anterior compartment myopathy / dysferlin-positive SCID / limb-girdle muscular dystrophies / metabolic diseases / autosomal recessive muscular dystrophy / Miyoshi’s myopathy / control SCID / inflammatory onset / A/J SCID / Donor deficiency / inflammatory / fibrosis / muscular dystrophy / scid/scid / Miyoshi myopathy / slowly progressive muscular disease / autosomal recessive limb-girdle muscular dystrophies / limbgirdle muscular dystrophy 2B / distal posterior myopathy / recessive limb girdle muscular dystrophy / dissociation / inflammatory activity / both AJ/SCID / distal anterior myopathy / Disease / SCID BL/AJ / intense inflammatory reaction / Dysferlin deficiency / dystrophin deficiency / few inflammatory signals / limb girdle muscular dystrophy / muscular dystrophies / dysferlin-deficient murine model SCID / SCID / MAB-transplanted SCID / inflammatory signals / /

MedicalTreatment

stem cell therapy / incision / renal transplants / heart transplants / cell therapy / gene therapy / /

Organization

University of Milan / Neurology Department / European Federation of Neurological Societies / Ministry of Health / National Institute of Health / San Raffaele Scientific Institute / Division of Regenerative Medicine / 2Neuromuscular Diseases Unit / San Raffaelle Institutional Review Board / Italian Ministry of Research and Health / Universitat Auto`noma de Barcelona / /

Person

Ann Neurol / Isabel Gemio / Dino Ferrari / Bl / /

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Position

Prime Minister / RT / *Corresponding author / WB / Bronson RT / Goolsby H et al / model / /

Product

FS / Sigma / gentamicin / Milan / penicillin / BMP-2 / MAB injection / D16 / membrane repair / /

ProvinceOrState

Prince Edward Island / /

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FM 4 / /

Technology

Neuroscience / BMP / cell therapy / stem cells / Exercise protocols / alpha / using TRIzol protocol / antibodies / Biotechnology / cloning / exercise training protocol / transplantation / cell therapy protocol / gene therapy / laser / lasers / Regenerative Medicine / /

URL

www.nature.com/cddis / http /

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