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An Optimized Triple Modality Reporter for Quantitative In Vivo Tumor Imaging and Therapy Evaluation Rachel A. Levin1., Csilla N. Felsen1., Jin Yang1, John Y. Lin1, Michael A. Whitney1, Quyen T. Nguyen2, Roger Y. Tsien1,3
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Document Date: 2016-09-12 23:26:04


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File Size: 2,88 MB

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City

Mountain View / GSG / La Jolla / Los Angeles / /

Company

Life Technologies / Caliper Life Sciences / Millipore / Sigma-Aldrich / Proc Natl Acad Sci U S A / PLOS ONE / Cell Signaling Technologies / BD Biosciences / Bio-Rad / Corning / IgG / Siemens Preclinical Solutions / GenBank / Vivo Imaging Solutions / Beckman Coulter / Creative Commons / /

Continent

America / /

Country

United States / /

/

Event

FDA Phase / /

Facility

terminus of MMAF / Howard Hughes Medical Institute / UCLA Crump Institute / University of California Los Angeles / Stanford University / Hormel Institute / David Stout laboratory / University of California San Diego / The David Stout laboratory / Laboratory Animals / University of Minnesota / Crump Institute / /

IndustryTerm

molecular imaging modality / nuclear noninvasive imaging / free software / virus-containing media / phosphate / animal imaging center design / fluorescence imaging / imaging / oxygen carrier gas / microPET imaging / bioluminescent imaging / bioluminescence optical imaging / far-red imaging settings / bioluminescence imaging / pooled virus-containing media / fresh viral production media / reagents/materials/analysis tools / viral media / intravital imaging / In vivo optical imaging / noninvasive imaging technologies / final solution / fluorescent imaging / molecular imaging / oil objective / media containing polyethylenimine / linker technology / fluorescence resonance energy transfer / viral production media / in vivo tumor imaging / animal live imaging / tumor imaging / /

MedicalCondition

ex vivo tumor / woodchuck hepatitis virus / triple reporter cancer / Sub-palpable* Tumors / breast cancer / type herpes / additional tumor / cells/tumor / tumor / internal tumor / large tumors / cancer / tumors / internal tumors / Real-time cancer / human cancer / bilateral tumors / subcutaneous tumor / cancer cells / murine orthotopic pancreatic cancer / E2-Crimson tumors / triple reporter tumor / bladder tumors / subpalpable tumors / small murine tumors / only necrotic tumor / vesicular stomatitis / triple reporter tumors / orthotopic tumors / metastasis / vivo tumor / human breast cancer tumors / herpes / multi-gene deficiency / J Cancer / small tumors / human breast cancer / human fibrosarcoma cell lines / bioluminescent cancer / cells/ tumor / human bladder cancer / tumor bioluminescence signal / reliably palpable tumors / tumor fluorescence signal / single cancer / reporter tumor / tumor metastasis / fibrosarcoma cancer / accurate tumor / /

MedicalTreatment

surgery / Head and Neck Surgery / /

Organization

Division of Otolaryngology/ / Foundation of Research / Science and Technology New Zealand / UCSD School of Medicine / Ecole Polytechnique Fe´de´rale de Lausanne / University of California San Diego / UCLA / National Institute of Health / UCSD Institutional Animal Care and Use Committee / Crump Institute for Molecular Imaging / Department of Pharmacology / UCLA Crump Institute for Molecular Imaging / Hormel Institute / LP (IFP) / Stanford University / University of California Los Angeles / UCLA Institutional Animal Care and Use Committee / Committee on the Ethics of Animal Experiments / Burrough-Wellcome Fund / Howard Hughes Medical Institute / University of Minnesota / /

Person

Athymic / Didier Trono / Qing Xiong / John Ngo / Perla Arcaira / Sanjiv Gambhir / Michael Z. Lin / /

Position

original author / final triple modality reporter / multi-reporter / Head / Enos RT / Author / Professor / triple reporter / Workman / representative / optimized triple reporter / Editor / Optimized Triple Modality Reporter / multi-modality reporter / triple modality reporter / e97415 Triple Reporter / An Optimized Triple Modality Reporter / reporter / /

Product

Sigma / Opti / glycine / penicillin / isoflurane / ganciclovir / adenosine / S04011 / /

ProvinceOrState

Minnesota / California / /

PublishedMedium

PLoS ONE / /

RadioStation

Loening AM / /

SportsLeague

Stanford University / /

TVStation

Wttk / /

Technology

linker technology / Cell Signaling Technology / drug delivery / Biomaterials / gene expression / noninvasive imaging technologies / tomography / antibodies / Biotechnology / cloning / laser / /

URL

www.plosone.org / /

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