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Microsome
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31 $Pharmacokinetics / Metabolism / Pharmacy / Medicinal chemistry / Microsome / Cytochrome P450 / S9 fraction / Hepatocyte / CYP3A4 / Pharmaceutical sciences / Pharmacology / Biology$	Lee xen0021.tex V2[removed]Metabolic stability screen in drug discovery Add to Reading List Source URL: media.wiley.com Language: English - Date: 2013-12-07 04:35:54 Pharmacokinetics Metabolism Pharmacy Medicinal chemistry Microsome Cytochrome P450 S9 fraction Hepatocyte CYP3A4 Pharmaceutical sciences Pharmacology Biology
32	Figure 3. General Scheme of Model-Based Prediction: The Investigational Drug (and Metabolite Present at ≥25% of Parent Drug AUC) as an Interacting Drug of CYP Enzymes CYP induction CYP inhibition (reversible and time-d Add to Reading List Source URL: www.fda.gov Language: English Biology Enzymes Pharmacokinetics Enzyme inhibitors Pharmacology Enzyme Microsome Physiologically based pharmacokinetic modelling Chemistry Metabolism Pharmaceutical sciences
33	Update of 2012 FDA Draft Guidance on Drug Interactions: Model-based Strategy to Integrate Knowledge and Quantify Effects Add to Reading List Source URL: www.fda.gov Language: English Biology Membrane biology Microsome Physiologically based pharmacokinetic modelling Cytochrome P450 Simcyp Simulator Pharmacokinetics Pharmacology Pharmaceutical sciences
34	Predicting Transporter Drug-Drug Interaction Using PBPK: Impact of Variability in In Vitro Data Perspective Add to Reading List Source URL: www.fda.gov Language: English Chemistry Pharmacy Metabolism Physiologically based pharmacokinetic modelling Toxicokinetics Enzyme Microsome Didanosine Simcyp Simulator Pharmaceutical sciences Pharmacology Pharmacokinetics
35	Interaction of 2,4-Dichlorophenoxyacetic Acid, Ethylene Chlorohydrin and Glutathione in the Stability of the Microsomal Ribonucleic Acid of Excised Cotton Cotyledons Add to Reading List Source URL: digital.library.okstate.edu Language: English - Date: 2009-01-09 17:02:30 Antioxidants Glutathione Peptides Thiols Plant physiology Plant hormone Auxin Microsome Ethylene Biology Chemistry RNA
36	p-Nitrophenol UDP Glucuronyltransferase and Epoxide Hydrase in Microsomes from Liver of Rats Fed 2-Acetylaminofluorene and Barbital Add to Reading List Source URL: digital.library.okstate.edu Language: English - Date: 2009-01-09 17:05:34 Amides Carcinogens Styrene oxide Glucuronosyltransferase Microsome Chemistry Biology 2-Acetylaminofluorene
37	PDF Document Add to Reading List Source URL: media.wiley.com Language: English - Date: 2008-02-21 05:01:42 Medicine Pharmacokinetics Metabolism Cytochrome P450 Toxicology Microsome Drug interaction CYP3A4 Drug metabolism Biology Pharmacology Pharmaceutical sciences
38	499 Index a 6 Å Rule 243–245 – demonstration 244 Add to Reading List Source URL: www.wiley-vch.de Language: English - Date: 2014-06-05 21:03:15 Pharmacokinetics Medicinal chemistry Metabolism Pharmacy Cytochrome P450 Microsome CYP3A4 Enzyme Drug metabolism Pharmaceutical sciences Chemistry Pharmacology
39	V Contents List of Contributors XVII Preface XXI A Personal Foreword XXIII Add to Reading List Source URL: www.wiley-vch.de Language: English - Date: 2014-06-05 21:03:14 Pharmacokinetics Cytochrome P450 Metabolism Medicinal chemistry Quantitative structure–activity relationship CYP3A4 Microsome Drug metabolism ADME Pharmaceutical sciences Chemistry Pharmacology
40	THE JOURNAL OF BIOLOGICAL CHEMISTRY © 2001 by The American Society for Biochemistry and Molecular Biology, Inc. Vol. 276, No. 12, Issue of March 23, pp. 8825–8828, 2001 Printed in U.S.A. Add to Reading List Source URL: www.petercsermely.linkgroup.hu Language: English - Date: 2011-03-17 14:48:34 Orthomolecular medicine Glutathione dehydrogenase Glutathione Vitamin C Microsome Dehydroascorbic acid Disulfide bond Thiol Chemistry Organic acids Antioxidants

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