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PLoS BIOLOGY Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2 Morris E. Feldman1, Beth Apsel1, Aino Uotila2, Robbie Loewith2, Zachary A. Knight1¤, Davide Ruggero3,
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Document Date: 2011-06-08 05:03:15


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Company

Creative Commons / /

Country

Switzerland / United States / /

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Facility

Howard Hughes Medical Institute / University of Geneva / University of California San Francisco / Salk Institute / Rockefeller University / /

IndustryTerm

active site / pharmacological tool / cancer therapies / treatment of cancer / pharmacological tools / internal ribosome entry site / viral internal ribosome entry site / important site / /

MedicalCondition

cancers / cancer / serum starvation / human disease / dissociation / /

MedicalTreatment

immunosuppression / cancer therapies / /

Organization

National Institute of Health / University of California San Francisco / San Francisco / Rockefeller University / New York / School of Medicine / Salk Institute for Biological Studies / Department of Molecular Biology / University of Geneva / Helen Diller Family Comprehensive Cancer Center / Department of Cellular and Molecular Pharmacology / Howard Hughes Medical Institute / Department of Urology / /

Person

Tony Hunter / /

Position

Author / original author / well-established bicistronic reporter / Major / representative / reporter / www.plosbiology.org Academic Editor / /

Product

PP242 / /

ProvinceOrState

New York / /

PublishedMedium

the PLoS Biology / PLoS Biology / Molecular Biology / /

Technology

alpha / recombination / apoptosis / cmp / /

URL

www.plosbiology.org / /