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Mammalian target of rapamycin / Sirolimus / P70S6 kinase / Autophagy / Tuberous sclerosis / RHEB / AKT / GTPase / Ras subfamily / Biology / Cell biology / Signal transduction


902 Biochemical Society TransactionsVolume 41, part 4 Nutrients and growth factors in mTORC1 activation Alejo Efeyan and David M. Sabatini1
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Document Date: 2015-04-21 13:21:13


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City

Kalaany / Cambridge / Kozma / /

Company

BP / J. and Cantley L.C. / Komatsu / Sabatini D.D. / /

Country

United States / /

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Event

Product Issues / /

Facility

Broad Institute of Harvard / Howard Hughes Medical Institute / David H. Koch Institute / David M. Sabatini1 Whitehead Institute / Ragulator complex / Massachusetts Institute of Technology / Cambridge Center / /

IndustryTerm

machinery / lysosomal nutrient-sensing machinery / energy / /

MedicalCondition

tumor / novel human primary immunodeficiency syndrome / mental retardation / cancer / Lindau disease / tumors / disease / early neonatal starvation / seizures / prolonged starvation / cysts / benign and malignant tumours / physiological setting Tuberous sclerosis / diabetes / neurofibromatosis / liver hemangiomas / starvation / tuberous sclerosis syndrome / tuberous sclerosis / human diseases / human syndrome / human disease / /

Organization

David H. Koch Institute / Cambridge Center / MIT / Harvard / Department of Biology / Massachusetts Institute of Technology / David M. Sabatini1 Whitehead Institute for Biomedical Research / Broad Institute / Charles A. King’s Trust / Howard Hughes Medical Institute / /

Person

Zhang / Simeon J. Fortin / Nat / Van den Ouweland / Charles A. King / Kwiatkowski / Alejo Efeyan / Rheb / /

Position

mediator / Carpenter / D.J. / /

Product

mice / /

ProvinceOrState

South Carolina / New York / Massachusetts / /

PublishedMedium

Biochemical Society Transactions / /

Technology

stem cells / /

URL

www.biochemsoctrans.org / /

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