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Signal transduction / Gene expression / Mammalian target of rapamycin / Proteins / Immunosuppressants / Sterol regulatory element-binding protein / Insulin-like growth factor 1 / Sirolimus / AKT / Biology / Biochemistry / Transcription factors


Cell Science at a Glance 1 Regulation of mTORC1 and its impact on gene
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Document Date: 2015-04-21 13:21:14

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File Size: 1,42 MB

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City

Santos / Kozma / Gray / L. A. / /

Company

Gould / BP / Matsuda / mTOR / Carpenter A. E. / Biologists Ltd / Carr S. A. / Gygi S. P. / Sabatini D. D. / mTORC1 / B. D. and Cantley L. C. / Sarbassov D. D. / Carmack A. E. / Pearson / Cantley L. C. / J. and Reeves S. A. / J. and Cantley L. C. / Kang S. A. / M. Sa / /

Country

United States / Canada / /

Currency

pence / /

/

Facility

Howard Hughes Medical Institute / Canadian Institute of Health Research / Nine Cambridge Center / Whitehead Institute / Massachusetts Institute of Technology / FKBP12rapamycin complex / ATPase complex / /

IndustryTerm

metabolic gene regulatory network / produce energy / treatment of cancers / online version / energy / energy production / Online Article / energy metabolism / sclerosis complex gene products / /

MedicalCondition

Myopathy / metastasis / lysosomal dysfunction / human cancers / cirrhosis / related diseases / melanoma / starvation / obesity / tuberous sclerosis / human diseases / obesity-linked insulin resistance / age-related diseases / breast cancer / cancers / tumor / Mitochondrial dysfunction / insulin resistance / cancer / disease / innate inflammatory response / chronic treatment / chronic mTORC1 inhibition / nonalcoholic fatty liver disease / Rapamycin-induced insulin resistance / tumour / diabetes / tuberous sclerosis complex / heart failure / tuberous sclerosis tumor / liver cancer / diseases / several human diseases / neurodegenerative diseases / deficiency / pulmonary lymphangioleiomyomatosis / diet-induced obesity / /

Organization

National Institute of Health / Internal Revenue Service / Department of Biology / Massachusetts Institute of Technology / Canadian Institute of Health Research / Universite´ Laval / US Federal Reserve / Centre de Recherche de l’Institut Universitaire de Cardiologie / Koch Center for Integrative Cancer Research / Nine Cambridge Center / Howard Hughes Medical Institute / Natural Sciences and Engineering Research Council of Canada / Canadian Liver Foundation / Whitehead Institute for Biomedical Research / /

Person

Murphy / Erle / Nat / Kim / Hashimoto / Kwiatkowski / Hee Um / Chen / Hudson / Albert / V / Krymskaya / V / Ferron / Hotamisligil / /

Position

investigator / D. J. / V. P. / /

Product

Skullcandy G.I. Headphone/Headset / simvastatin / glucagon / gemfibrozil / /

ProvinceOrState

South Carolina / Laguna / Nova Scotia / M. B. / A. B. / /

PublishedMedium

PLoS ONE / /

Technology

alpha / JPEG / stem cells / DNA binding / apoptosis / gene expression / /

URL

http /

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