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Peripheral membrane proteins / Genes / Proteins / Tuberous sclerosis protein / Mammalian target of rapamycin / G proteins / Guanine nucleotide exchange factor / GTPase / Sirolimus / Biology / Biochemistry / Signal transduction


TICB-1044; No. of Pages 7 Review Regulation of mTORC1 by amino acids Liron Bar-Peled1 and David M. Sabatini2,3,4,5
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Document Date: 2015-04-21 13:21:11

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City

La Jolla / Cambridge / /

Company

Toro / L. (2000) Dynein / Pages 7 Review / E.V. and Aravind / Wurmser A.E. / Elsevier Ltd. / /

Country

United States / /

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Facility

Broad Institute of Harvard / USA Whitehead Institute / Howard Hughes Medical Institute / Nine Cambridge Center / Gtr2p complex / Cambridge Center / Koch Institute / N terminus / GATOR complex / N terminus of Lamtor1 / Massachusetts Institute of Technology / EGO Complex / TSC complex / The Scripps Research Institute / Ccz1 complex / /

IndustryTerm

energy levels / Mammalian systems / cell culture media / machinery / cellular energy response / chemical inhibitors / amino acid sensing machinery / light chains / hormonal signaling networks / /

MedicalCondition

ovarian cancers / GDP dissociation / multiple myeloma cells / folliculin tumor / human tumors / amino acid starvation / Dube syndrome / polycystic kidneys / starvation / TSC1/TSC2 tumor / tuberous sclerosis / human diseases / resident candidate tumor / familial focal epilepsy / hamartomatous syndrome / glioblastoma / cancers / tumor / novel human primary immunodeficiency syndrome / cancer / tumors / disease / autosomal dominant focal epilepsies / RagB GDP dissociation / diabetes / trimeric tuberous sclerosis complex / previously unknown primary immune disorder / tuberous sclerosis complex / lung cancer / tuberous sclerosis tumor / diseases / questions starvation / epilepsy / epileptic seizure / several human diseases / deficiency / hamartoma-like syndrome / human disease / /

MusicGroup

Energy / /

Organization

Department of Chemical Physiology / Cambridge Center / USA Whitehead Institute for Biomedical Research / Damon Runyon Cancer Research Foundation / Harvard / Department of Biology / Massachusetts Institute of Technology / Broad Institute / Scripps Research Institute / Ragulator / Nine Cambridge Center / Department of Defense / Howard Hughes Medical Institute / Koch Institute for Integrative Cancer Research / /

Person

Nat / Shuyu Wang / Schroder / Minna / Lynne Chantranupong / Tom DeCesare / /

Position

investigator / scaffolding subunit Corresponding author / /

Product

ATPase / /

ProvinceOrState

RagA/B / RagC / California / Massachusetts / /

Technology

Proteomics / Cloning / Genotype / /

URL

http /

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