MTORC1

Results: 13



#Item
11Cullin / Autophagy / NEDD8 / CAND1 / BTRC / Tuberous sclerosis protein / Von Hippel–Lindau tumor suppressor / CUL1 / Ubiquitin / Biology / Proteins / Mammalian target of rapamycin

Targeting Cullin-RING ligases by MLN4924 induces autophagy via modulating the HIF1-REDD1-TSC1-mTORC1-DEPTOR axis

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Source URL: www.nature.com

Language: English - Date: 2012-09-06 06:12:07
12Signal transduction / Mammalian target of rapamycin / Immunosuppressants / Macrolides / AKT / Phosphoinositide 3-kinase / Sirolimus / GSK-3 / Phosphorylation / Biology / Biochemistry / Protein kinases

PLoS BIOLOGY Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2 Morris E. Feldman1, Beth Apsel1, Aino Uotila2, Robbie Loewith2, Zachary A. Knight1¤, Davide Ruggero3,

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Source URL: www.molbio.unige.ch

Language: English - Date: 2011-06-08 05:03:15
13Mammalian target of rapamycin / Signal transduction / Sirolimus / Glutamate dehydrogenase / SIRT4 / Sirtuin / Tuberous sclerosis / Glutaminolysis / Insulin-like growth factor 1 / Biology / Chemistry / Biochemistry

The mTORC1 Pathway Stimulates Glutamine Metabolism and Cell Proliferation by Repressing SIRT4 Alfred Csibi,1 Sarah-Maria Fendt,2,6 Chenggang Li,3,5 George Poulogiannis,4,5 Andrew Y. Choo,1 Douglas J. Chapski,1 Seung Min

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Source URL: www.lamhealthproject.org

Language: English - Date: 2013-05-10 11:41:23
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