View Document Preview and Link Document Date: 2008-02-21 05:54:50 Open Document File Size: 2,36 MB Share Result on Facebook
City specificity / New York / Berlin / Amsterdam / London / / Company LG / Proc Natl Acad Sci U S A / Oxford University Press / MRC Laboratory / O2 / Creative Commons / Cold Spring Harbor Laboratory Press / Stephens / O1 / Teichmann SA / Kauffman SA / sequenPLoS Computational Biology / / / Event FDA Phase / / Facility MRC Laboratory of Molecular Biology / Sander J. Tans* FOM Institute / / IndustryTerm transcription control networks / mutant network / experimental network / ebg systems / Online Release / presented systematic search / protein networks / interaction network / gene regulatory network / lac operon products / heterodimer binding energy / trivial solutions / raf systems / evolutionary algorithm / regulatory networks / regulatory systems / inherent physico-chemical limitations / energy / duplicate network / non-palindromic operator / genetic network / symmetric network / genetic networks / gene expression networks / dimer-operator binding energy / biological regulatory networks / dimerization free energy / mammalian gene regulation networks / engineered gene networks / evolutionary search / dimerization energy / coevolutionary search / / Organization Fitness Optima / Sander J. Tans* FOM Institute for Atomic and Molecular Physics / Oxford University / / Person Hakim V / Pilar Francino / Ohno / Kobus Kuipers / Benno Mu / Yoshio Tateno / Frank J. Poelwijk / Harald Tepper / Dennis Bray / Daniel J. Kiviet / Sorin Tanase-Nicola / Sarah Teichmann / James Shapiro / / Position original author / Farmer / Author / candidate for the initial divergence pressure as well / www.ploscompbiol.org Editor / reporter / / Product S3 / S1 / S2 / / PublishedMedium PLoS Computational Biology / the PLoS Computational Biology / Molecular Biology / / RadioStation Sengupta AM / / Technology radiation / Bioinformatics / evolutionary algorithm / DNA binding / PDF / gene therapy / Directed evolution / gene expression / simulation / / URL www.ploscompbiol.org / / SocialTag 
Evolutionary Potential of a Duplicated Repressor-Operator Pair: Simulating Pathways Using Mutation Data Frank J. Poelwijk[, Daniel J. Kiviet[, Sander J. Tans* FOM Institute for Atomic and Molecular Physics (AMOLF), Amste