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Peptide hormones / Neuroendocrinology / Neuropeptides / Recombinant proteins / Endocrinology / Kisspeptin / Gonadotropin-releasing hormone / Hypothalamic–pituitary–gonadal axis / Puberty / Biology / Endocrine system / Medicine


REVIEW ARTICLE published: 24 January 2012 doi: [removed]fendo[removed]
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Company

PI3K / NEUROPEPTIDE SYSTEMS / /

Country

United States / Israel / /

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Event

Product Issues / /

Facility

National Institute of Health / Institute of Experimental Medicine / Stony Brook University / University of Toledo College / University of Cordoba / /

IndustryTerm

energy deficit / food-restricted female rats / treatment of metabolic and reproductive disorders / energy status / positive energy status / food restriction / energy homeostasis / chronic and acute food restriction / food / energy balance / chronic food restriction / chemical inhibition / food-restricted animals / increased food intake / food intake / negative energy balance delay puberty / negative energy balance / positive energy balance / /

MedicalCondition

ovarian Infertility / LY294002 partially suppressed lordosis / chronic low-grade inflammation / DIO-induced infertility / hyperinsulinemia / chronic immune signals / undernutrition / chronic subnutrition / menstrual dysfunction / chronic food restriction / dysfunction / PI3K regulatory Kisspeptin-cell specific deletion subunit p85α Results References Infertility / chronic exposure / STZ-induced diabetes / miscarriages / metabolic and reproductive disorders / obesity / polycystic ovarian syndrome / metabolic dysfunction / tuberous sclerosis / delayed puberty / hypothalamic hypogonadism / metabolic disorders / reproductive disorder / chronic and acute food restriction / precocious puberty / reasons childhood obesity / infertility / malnutrition / Adaptor protein Hypothalamic deletion Infertility / insulin resistance / clear data linking obesity / chronic inflammatory state / male monkey unknown diabetes / metabolic diseases / anorectic disorders / hyperglycemia / erectile dysfunction / mild obesity / zona / peripheral insulin resistance / diabetes / sickness / secondary hypogonadism / metabolic syndrome / DIO display fasting hyperglycemia / hyperandrogenism / female reproductive disorders / eating disorders / anorexia nervosa / Global KO Infertility / reproductive disorders / Diet-induced obesity / HFD-induced obesity / reproductive dysfunction / Chronic i.c.v. infusion / disorders / lordosis / /

MedicalTreatment

caloric restriction / hormone replacement / /

Organization

Administration of IGF-1 / University of Toledo College of Medicine / National Institute of Health / Internal Revenue Service / Department of Physiology and Biophysics / Stony Brook University / University of Cordoba / Maricedes Acosta-Martínez* Department of Physiology and Biophysics / US Federal Reserve / Medical Center / Institute of Experimental Medicine / /

Person

Burt Solorzano / Raul Miguel Luque Huertas / Csaba Fekete / /

Position

mediator / Carpenter / messenger / /

Product

estradiol / testosterone / spermatogenesis / ovarian Infertility / PI3K pathway / PI3K signaling / leptin-stimulated hypothalamic STAT3 phosphorylation / /

ProvinceOrState

New York / /

Technology

alpha / cell receptors / cell signaling / gene expression / gene targeting / /

URL

www.frontiersin.org / /

SocialTag