| Document Date: 2013-11-13 13:13:53
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City Seville / Reference / / Company Pharmacyclics / Alteon Inc. / / Country United States / / Currency pence / / Event FDA Phase / / IndustryTerm active site / grapefruit products / chemical name / excretion product / treatment of patients with mantle cell lymphoma / food / / MedicalCondition Dizziness Headache / abdominal pain / Epistaxis / pneumonia / General disorders / Rash Petechiae / hypertension / recurrent B-cell lymphoma / nutritional disorders Decreased appetite Dehydration / rash / abdominal pain / disease / Arthralgia / headache / dyspnea / intracranial hemorrhage / hematuria / mantle cell lymphoma / Musculoskeletal pain Muscle spasms / Carcinogenesis / respiratory tract infection Urinary tract infection Pneumonia Skin infections Sinusitis / cellulitis / neutropenia / nausea / thrombocytopenia / subdural hematoma / lymphocytosis / fever / lethargy / vomiting / pain / fatigue / thoracic and mediastinal disorders / skin infections / skin cancers / diarrhea / atrial fibrillation / infection / non-fatal infections / carcinomas / renal failure / Cough / constipation / Infections / anemia / upper respiratory tract infection / dehydration / / MedicalTreatment antibiotics / surgery / dialysis / / Organization CYP3A Inducers Administration of IMBRUVICA / DOSAGE AND ADMINISTRATION / FDA / / / Position Major / General / / Product efavirenz / phenytoin / itraconazole / carbamazepine / ketoconazole / dimethyl sulfoxide / clarithromycin / erythromycin / ciprofloxacin / rifampin / fluconazole / IMBRUVICA / / Technology Pharmacokinetics / Pharmacodynamics / dialysis / / URL www.fda.gov/medwatch / /
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IMBRUVICATM (ibrutinib) capsules