IC50

Results: 120



#Item
41Metabolism / Biochemistry / Catalysis / Enzyme inhibitors / Pharmacology / Enzyme kinetics / IC50 / Enzyme / Non-competitive inhibition / Chemistry / Enzymes / Biology

7274 J. Med. Chem. 2006, 49, [removed]Interpreting Steep Dose-Response Curves in Early Inhibitor Discovery

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Source URL: shoichetlab.compbio.ucsf.edu

Language: English - Date: 2013-10-15 11:56:41
42Colloidal chemistry / Protein families / Integral membrane proteins / Signal transduction / Pic50 / Arrestin / G protein-coupled receptor / Colloid / IC50 / Biology / Chemistry / Membrane biology

Article pubs.acs.org/jmc Colloidal Aggregation Causes Inhibition of G Protein-Coupled Receptors Maria F. Sassano,†,⊥ Allison K. Doak,‡,⊥ Bryan L. Roth,*,† and Brian K. Shoichet*,‡

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Source URL: www.ncbi.nlm.nih.gov

Language: English
43Metabolism / Enzymes / Medicinal chemistry / Enzyme inhibitors / Enzyme / IC50 / Reverse-transcriptase inhibitor / High-throughput screening / Drug discovery / Pharmaceutical sciences / Chemistry / Pharmacology

doi:[removed]j.drudis[removed]

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Source URL: shoichetlab.compbio.ucsf.edu

Language: English - Date: 2013-10-15 11:56:45
44Receptor antagonist / Insulin-degrading enzyme / Ligand / Agonist / G protein-coupled receptor / Receptor / Allosteric regulation / IC50 / NMDA receptor / Biology / Cell biology / Cell signaling

0026-895X[removed]–72$3.00 MOLECULAR PHARMACOLOGY Copyright © 2002 The American Society for Pharmacology and Experimental Therapeutics Mol Pharmacol 61:65–72, 2002 Vol. 61, No. 1

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Source URL: med.stanford.edu

Language: English - Date: 2009-12-04 19:09:07
45Cell signaling / Membrane biology / Proteins / Receptor antagonist / Ligand / Agonist / G protein-coupled receptor / Receptor / IC50 / Biology / Pharmacology / Signal transduction

THE JOURNAL OF BIOLOGICAL CHEMISTRY © 2003 by The American Society for Biochemistry and Molecular Biology, Inc. Vol. 278, No. 1, Issue of January 3, pp. 352–356, 2003 Printed in U.S.A.

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Source URL: med.stanford.edu

Language: English - Date: 2009-12-04 19:09:08
46IC50 / Median lethal dose / Toxicology / Mole

US EPA/Appendix G; Standard Test Reporting Template

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Source URL: www.epa.gov

Language: English - Date: 2009-10-02 11:23:01
47IC50 / Median lethal dose / Toxicology / Mole

US EPA/Appendix G; Standard Test Reporting Template

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Source URL: www.epa.gov

Language: English - Date: 2009-10-02 11:23:01
48Xenotransplantation / IC50 / Osteosarcoma / Medicine / Sarcoma / Ewing sarcoma

Pediatric Preclinical Testing Program (PPTP) evaluation of the Akt inhibitor GSK690693 #3193 Hernan Carol1, Richard B. Lock1, Peter J. Houghton2, Christopher L Morton2, John M. Maris3, Joshua Courtright3, E. Anders Kolb

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Source URL: pptp.nchresearch.org

Language: English - Date: 2009-12-15 10:12:13
49Brain tumor / Anatomical pathology / Neuroblastoma / Ewing sarcoma / Rhabdomyosarcoma / IC50 / Medicine / Oncology / Sarcoma

# 5358 PEDIATRIC PRECLINICAL TESTING PROGRAM (PPTP) EVALUATION OF THE NONCAMPTOTHECIN TOPOISOMERASE 1 TARGETED AGENT GENZ[removed]Peter J. Houghton1, Richard B. Lock2, Hernan Carol2, Christopher L Morton3, Richard Gorlic

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Source URL: pptp.nchresearch.org

Language: English - Date: 2011-03-31 16:26:53
50Nutrients / Genetics / Assay / Biochemistry / Titration / IC50 / Phytoestrogens / Receptor antagonist / FACT / Biology / Chemistry / Laboratory techniques

Draft Report on the Current Status of Test Methods for Detecting Endocrine Disruptors: In Vitro Estrogen Receptor Transcriptional Activation Assays - April 2002

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Source URL: www.epa.gov

Language: English - Date: 2007-11-01 13:24:47
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