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Cell biology / Protein domains / Two-component regulatory system / Scaffold protein / SH3 domain / Histidine kinase / CRK / Cell surface receptor / Src / Biology / Signal transduction / Cell signaling


Engineering robust control of two-component system phosphotransfer using modular scaffolds Weston R. Whitakera,b, Stephanie A. Davisc, Adam P. Arkinb,d,e,1, and John E. Dueberb,d,e,1 a The University of California, Berk
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Document Date: 2014-06-23 18:52:12


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RBS / Lawrence Berkeley National Laboratory / Chapman SA / ACS / Keating AE / GE Healthcare / Ligand / Lindner AB / Knudsen / Friedland AE / TCSs / /

Currency

pence / /

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Facility

Princeton University / SH3pep-LZB scaffold / C terminus / KSR scaffold / The Ste5 scaffold / Ste5 scaffold / eEnergy Biosciences Institute / University of California / C terminus of Taz / /

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sensory machinery acts / ribosome-binding site / signal transduction systems / multicellular computing / biological systems / recruitment machinery / multilayer processing / web server / regulatory networks / natural eukaryotic systems / protein interaction devices / analysis software / synthetic biology applications / gene networks / /

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P.A. / S.A.D. / /

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Laub MT / /

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National Science Foundation / Princeton University / University of California / Berkeley / eEnergy Biosciences Institute / University of California / San Francisco / /

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Michael Laub / Activation / Adam P. Arkinb / Weston R. Whitakera / Stephanie A. Davisc / John E. Dueberb / /

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Author / CpxR reporter / Representative / reporter / /

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Crk SH3 / /

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J / /

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New Jersey / California / /

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Nature Protocols / /

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Sloot AM / /

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CBET / /

Technology

protein engineering / X-ray / gene expression / cell signaling / recombination / web server / /

URL

www.pnas.org/cgi/doi/10.1073/pnas.1209230109 / www.pnas.org/lookup/suppl/doi / /

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