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Spliceosome / RNA splicing / Gene expression / Molecular biology / Intron / Messenger RNA / Group II intron / SnRNP / Precursor mRNA / RNA / Genetics / Biology


Journal of Biomolecular Screening http://jbx.sagepub.com/ A High-Throughput Splicing Assay Identifies New Classes of Inhibitors of Human and Yeast Spliceosomes
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Document Date: 2013-06-27 00:38:00

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Sunnyvale / Foster City / Waltham / /

Company

PerkinElmer / /

Country

United States / /

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pence / /

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Facility

National Cancer Institute / E/H complex / E complex / C complex / B complex / University of California Santa Cruz / Laboratory Automation / A/B/C complex / A complex / /

IndustryTerm

chemical probes / chemical libraries / chemical features / large chemical libraries / gene products / chemical steps forming / online version / yeast splicing systems / machinery / chemotherapeutic applications / chemical structures / no-spliced mRNA product / /

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SANTA CRUZ / /

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National Cancer Institute / Center for Molecular Biology of RNA / UNIV OF CALIFORNIA SANTA CRUZ / Department of Molecular Cell and Developmental Biology / Department of Chemistry and Biochemistry / Society for Laboratory Automation / University of California Santa Cruz / Santa Cruz / /

Person

Rhonda J. Perriman / Manuel Ares Jr. / Walter M. Bray / Compounds Inhibit / Kerstin A. Effenberger / Melissa S. Jurica / R. Scott Lokey / Manuel Ares / Jr. / /

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fluorophore reporter / RT / Corresponding Author / Candidate / /

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California / /

Technology

chemical libraries / gene expression / High-throughput screening / gel electrophoresis / apoptosis / /

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http /

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