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Nervous system / Neuroscience / Neurology / Astrocyte / Minocycline / Microglia / Neuroglia / Caspase 3 / Glial fibrillary acidic protein / Biology / Proteins / Glial cells


Astrocytes are important mediators of Aβ-induced neurotoxicity and tau phosphorylation in primary culture
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Document Date: 2011-06-02 05:51:37

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Welwyn Garden City / Dorset / Southampton / Vartiainen / Minneapolis / Bretteville / Ely / Cambridge / London / Paisley / /

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IgG / Carl Zeiss Inc. / Li-Cor Biosciences / Wellcome Trust / elevated Ab. / Millipore / California Peptide Co. / Graphpad Software Inc. / oligomeric Ab / mM Ab / Creative Commons / 10 mM Ab / Macmillan Publishers Limited / /

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United States / United Kingdom / /

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Product Issues / /

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Institute of Psychiatry / Scale bar / King’s College / Albert Einstein College of Medicine / /

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treatment of AD and related neurodegenerative diseases / treatment of AD and related neurodegenerative disorders / media amounts / tau cleavage product / abnormal processing / cytokine media amounts / infrared imaging system / aberrant tau processing / abnormal tau processing / /

MedicalCondition

inflammatory response / several inflammatory mediators / major depressive disorder / Neuroscience Alzheimer’s disease / tumour necrosis / dementia / inflammatory factors / neurodegenerative disease / brain injury / selected inflammatory cytokines / inflammatory cytokine / inflammatory mediators / tauopathy / inflammatory cytokines / synaptic dysfunction / inflammatory cell activation / neurodegenerative disorders / neurodegenerative disorder / specific inflammatory cytokines / tauopathies / Alzheimer’s disease / Disease / Wyss-Coray T. Inflammation / several inflammatory cytokines / astrocytic inflammatory responses / astrocyte-mediated inflammatory responses / mild cognitive impairment / related disorders / memory deficits / Alzheimer disease / neurodegenerative diseases / individual inflammatory cytokines / Inflammation / inflammatory mediator / tumour necrosis factors / Microglial dysfunction / inflammatory immune system activation / inflammatory responses / inflammatory / /

Organization

MRC Centre for Neurodegeneration Research / King’s College London / Medical Research Council / Alzheimer’s Society / Institute of Psychiatry / Albert Einstein College of Medicine / Department of Neuroscience / Henry Smith Charity / /

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Neuroscience Alzheimer / Peter Davies / Pierce Endogen / Van Eldik / /

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triple transgenic animal model / *Corresponding author / inflammatory mediator / mediator / Mattson MP / Vitek MP / Representative / /

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sodium chloride / IL-13 / IL-1ra / IL-6 / IL-1b / IL-17 / beta-amyloid clearance pathways / /

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LaFerla FM / Kennedy AM / Kinsey AM / Lynch AM / /

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antibodies / Cell Signaling / apoptosis / drug discovery / /

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