Fleming / Omniox Inc. / Protein Data Bank / G.T.K. S.L. A.S. / Karnoub AE / Nikon / Other GTPase Binding Partners / Keating AE / /
Country
Hungary / China / /
Currency
pence / / /
Event
FDA Phase / /
Facility
orthoITSN complex / National Institute of Health / Medical Science College / China Three Gorges University / University of Washington / Institute of Molecular Biology / eHoward Hughes Medical Institute / Mena complex / Eötvös Loránd University / University of California / /
IndustryTerm
designed interface site / cellular systems / polar networks / protein network / protein-protein interaction networks / reagents/analytic tools / potential solution / fixed backbone protocol / cellular protein interaction network / machinery / endogenous signaling networks / intensive remodeling protocol / cellular machinery / sequence tolerance protocol / lowest energy structure / flexiblebackbone remodeling protocols / signal transduction networks / energy functions / functional interaction networks / energy / computational second-site suppressor protocol / polar interaction network / orthogonal systems / protein engineering applications / relative free energy differences / engineerable site / hydrogen bond network / important applications / described protocol / energy hot spots / intensive backbone remodeling protocol / suppressor protocol / synthetic oscillatory network / /
Organization
National Institute of Health / Institute of Molecular Biology / National Science Foundation / eHoward Hughes Medical Institute / Department of Bioengineering and Therapeutic Sciences / University of California / Berkeley / China Three Gorges University / Department of Biochemistry / Sandler Foundation / Medical Science College / University of Washington / Seattle / University of California / San Francisco / Department of Molecular and Cellular Pharmacology / Eötvös Loránd University / /
Person
Peter Hwang / Alex Watters / James Onuffer / Jason Park / Colin Smith / Tanja Kortemmea / Attila Reményic / Ben Rhau / Kris Kuchenbecker / Brian J. Yehc / Orion Weiner / Derek T. Wongb / Farid Ahmad / David Baker / Benjamin Rhau / Gregory T. Kappa / Anselm Levskaya / Jack Tauntone / Wendell A. Lime / James S. Fraserc / /
Position
principal investigator / engineer / representative / /
SEE COMMENTARY Control of protein signaling using a computationally designed GTPase/GEF orthogonal pair Gregory T. Kappa,1,2, Sen Liua,1,3, Amelie Steina, Derek T. Wongb,c, Attila Reményic,4, Brian J. Yehc,d, James S.