| Document Date: 2009-03-31 15:48:48
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Company Disease Characteristics Characteristic Age Group / / Country United States / / Event FDA Phase / / IndustryTerm treatment for an IRESSA overdose and possible symptoms / food / treatment of non-small cell lung cancer / / MedicalCondition tumor / cancer / lymphoma / acne / tumors / disease / NSCLC / dyspnea / shortness of breath / Carcinogenesis / interstitial pneumonia / dysfunction / cerebral hemorrhage / nausea / skin rash / toxic epidermal necrolysis / fever / pulmonary fibrosis / hepatic metastases / conjunctivitis / vomiting / amblyopia / pulmonary / urticaria / angioedema / pancreatitis / allergic reactions / erythema multiforme / diarrhea / hypersensitivity / irritation / cough / Pruritus / metastases / pneumonitis / rash / interstitial lung disease / adenocarcinoma / dehydration / / MedicalTreatment radiation therapy / chemotherapy / chemotherapies / radiation / / Organization World Health Organization / Patients and DOSAGE AND ADMINISTRATION / DOSAGE AND ADMINISTRATION / / Product carboplatin / phenytoin / itraconazole / ranitidine / PHARMACOLOGYPharmacokinetics-Drug / paclitaxel / polyethylene glycol / acetic acid / sodium bicarbonate / ketoconazole / IRESSA / cimetidine / S-003 / / PublishedMedium the Japanese post / / Technology Pharmacokinetics / radiation / chemotherapy / /
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NDA[removed]S-003 Page 3 Rev[removed]