Cyclin

Results: 197



#Item
71Proteins / Cyclin-dependent kinase 5 / GAK

Microsoft Word - Publication2002

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Source URL: www.mnc.ust.hk

Language: English - Date: 2009-07-31 04:22:31
72Proteins / Molecular biology / Cellular processes / P-TEFb / RNA interference / DSIF / Cell cycle / Phosphatase / Cyclin-dependent kinase / Biology / Gene expression / RNA

CDK-9/cyclin T (P-TEFb) is required in two postinitiation pathways for transcription in the C. elegans embryo Eun Yong Shim,1,2 Amy K. Walker,1,2 Yang Shi,2 and T. Keith Blackwell1,2,3 1

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Source URL: blackwellweb.joslin.harvard.edu

Language: English - Date: 2003-07-07 15:30:54
73Proteins / CDK inhibitor / Ki-67 / Cyclin-dependent kinase / Cyclin / Biology / Cell biology / Cell cycle

Identification of a Predicted Biologically Effective Dose of AT7519, a Cyclin Dependent Kinase Inhibitor, in a Phase I Study[removed]M. S. Squires1, V. Lock1, J. Adam2 , D. Smith1, N. T. Thompson1, M. Yule1, J. F. Lyons1,

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Source URL: astx.com

Language: English - Date: 2012-12-13 18:06:00
74Cell cycle / CDK inhibitor / Cyclin-dependent kinase / Biomarker / Cyclin / Ovarian cancer / Ki-67 / Biology / Cell biology / Proteins

AT7519, a Selective Small Molecule Inhibitor of Cyclin Dependent Kinases: Pharmacodynamic Biomarker Activity in a Phase I Study. Author(s) MS Squires, PJ Sweeney, V Lock, NT Thompson, D Smith, EJ Lewis, NJ Gallagher, H C

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Source URL: astx.com

Language: English
75Proteins / Cell cycle / Apoptosis / Genes / B-cell chronic lymphocytic leukemia / CDK inhibitor / Poly ADP ribose polymerase / Cyclin-dependent kinase / Cyclin / Biology / Cell biology / Programmed cell death

AT7519, a Potent Multi-targeted CDK Inhibitor, is Active in CLL Patient Samples Independent of Stage 3161 V Lock1, L Cooke2, M Yule1, NT Thompson1, K Della Croce2, JF Lyons1,MS Squires1,D Mahadevan2. INTRODUCTION

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Source URL: astx.com

Language: English
76Proteins / Apoptosis / Cyclin / CDK inhibitor / Survivin / Retinoblastoma protein / B-cell chronic lymphocytic leukemia / Biology / Cell biology / Cell cycle

AT7519, A Potent CDK Inhibitor, is Active in Leukaemia Models and Primary CLL Patient Samples MS Squires1, RE Feltell1, V Lock1, D Smith1, EJ Lewis1, J Higgins1, M Yule1, NT Thompson1, L Cooke2, K Della Croce2, W Qi2, JF

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Source URL: astx.com

Language: English
77Beth Israel Deaconess Medical Center / Chemistry / MD4 / Bortezomib / MD6

A Phase 1/2 Open-Label Multicenter Study Of The Cyclin Kinase Inhibitor AT7519M Alone and In Combination With Bortezomib In Patients With Previously Treated Multiple Myeloma Abst. No. 1976

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Source URL: astx.com

Language: English - Date: 2013-12-09 05:38:21
78Cell cycle / Apoptosis / Tumor suppressor genes / Programmed cell death / SKP2 / Cyclin-dependent kinase 2 / Salinomycin / CDKN1B / Cyclin / Biology / Cell biology / Proteins

OPEN Citation: Cell Death and Disease[removed], e693; doi:[removed]cddis[removed] & 2013 Macmillan Publishers Limited All rights reserved[removed]www.nature.com/cddis

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Source URL: www.nature.com

Language: English - Date: 2013-06-27 09:56:01
79Proteins / Retinoblastoma protein / Cyclin / Apoptosis / CDK inhibitor / Cell cycle checkpoint / Protein P16 / Biology / Cell biology / Cell cycle

A Comparison of the Pharmacological Profile of AT7519 in Solid Tumour and Haematological Cell Lines. Author(s) MS Squires, R E Feltell, V Lock, D Smith, EJ Lewis, J Higgins, M Yule, D M Cross, NT Thompson, JF Lyons

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Source URL: astx.com

Language: English - Date: 2012-12-13 18:06:00
80Proteins / Mucositis / Chemotherapy / Cyclin-dependent kinase / Cyclin / Methadone / Biology / Cell biology / Cell cycle

ABSTRACT # 491 NCIC CTG IND.177: Phase I Study of AT7519M Given as a Short Infusion Twice Weekly S. J. Hotte, E. X. Chen, L. McIntosh, H. Hirte, S. Turner, A. Jarvi, V. Lock, L. Seymour

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Source URL: astx.com

Language: English - Date: 2012-12-13 18:06:00
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