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Crizotinib
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21	Public Summary Document – November 2014 PBAC Meeting 4.1 CRIZOTINIB 200 mg capsule, 60 and 250 mg capsule, 60; Add to Reading List Source URL: www.pbs.gov.au Language: English - Date: 2015-03-16 01:05:14 Crizotinib Organofluorides Pfizer Piperidines Pyrazoles Pyridines Anaplastic lymphoma kinase Non-small-cell lung carcinoma Pemetrexed Medicine Chemistry Organic chemistry
22	October 24, 2012 Astex Pharmaceuticals Announces Initiation of AT13387 Phase 2 Study in Non-Small Cell Lung Cancer DUBLIN, Calif., Oct. 24, 2012 (GLOBE NEWSWIRE) -- Astex Pharmaceuticals, Inc. (Nasdaq:ASTX), a pharmaceu Add to Reading List Source URL: astx.com Language: English Organofluorides Piperidines Lung cancer Crizotinib Pyrazoles Anaplastic lymphoma kinase Non-small-cell lung carcinoma Hsp90 Erlotinib Chemistry Organic chemistry Pfizer
23	Public Summary Document Application No[removed] – Testing of the anaplastic lymphoma kinase (ALK) gene in patients with non–small cell lung cancer to determine eligibility for treatment with crizotinib Add to Reading List Source URL: www.msac.gov.au Language: English - Date: 2015-04-16 01:23:53 Lung cancer Organofluorides Organochlorides Anatomical pathology Crizotinib Pyrazoles Non-small-cell lung carcinoma Anaplastic lymphoma kinase ALK inhibitor Medicine Chemistry Oncology
24	ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS 1 This medicinal product is subject to additional monitoring. This will allow quick identification of Add to Reading List Source URL: www.ema.europa.eu Language: English - Date: 2015-03-16 11:38:36 Lung cancer Crizotinib Piperidines Pyrazoles Pyridines Anaplastic lymphoma kinase Norfloxacin Non-small-cell lung carcinoma Pimozide Chemistry Organic chemistry Organofluorides
25	Microsoft Word[removed]FinalPSD-ALKtestingforcrizotinib-Nov2014update-accessible.DOCX Add to Reading List Source URL: www.msac.gov.au Language: English - Date: 2015-04-16 01:23:53 Lung cancer Organofluorides Organochlorides Anatomical pathology Crizotinib Pyrazoles Non-small-cell lung carcinoma Anaplastic lymphoma kinase ALK inhibitor Medicine Chemistry Oncology
26	November 2013 PBAC Meeting Outcomes - Deferrals Drug and Form Drug Use and Type Listing Requested by Sponsor PBAC Outcome and Comments Add to Reading List Source URL: www.pbs.gov.au Language: English - Date: 2015-01-19 17:21:09 Crizotinib Macular edema Anaplastic lymphoma kinase Macula of retina Non-small-cell lung carcinoma Progression-free survival Central retinal vein occlusion Medicine Ranibizumab Bevacizumab
27	ACTIVITY OF THE HSP90 INHIBITOR, AT13387, IN ALK-DRIVEN TUMOR MODELS. Nicola Wallis, Tomoko Smyth, Joanne Munck, Ana Rodriguez-Lopez, Victoria Lock, Rachel McMenamin, Neil Thompson & John Lyons Astex Pharmaceuticals, 436 Add to Reading List Source URL: astx.com Language: English - Date: 2012-12-17 16:09:22 Organofluorides Oncology Crizotinib Piperidines Pyrazoles Pyridines ALK inhibitor Anaplastic lymphoma kinase Non-small-cell lung carcinoma Lung cancer Medicine Chemistry
28	Drug Name, form(s), strength(s) and Sponsor Drug Type and Use Listing requested by Sponsor / Purpose of Submission PBAC Recommendation CRIZOTINIB, 200 mg capsule, 60 and 250 mg capsule, 60 Add to Reading List Source URL: www.pbs.gov.au Language: English - Date: 2015-01-19 17:21:09 Biology Ribbon symbolism Bevacizumab Trastuzumab Ranibizumab Pertuzumab Herpes zoster Crizotinib Breast cancer Medicine Monoclonal antibodies Pharmacology
29	Combination of HSP90 inhibitor onalespib (AT13387) with crizotinib to treat or delay resistance in NSCLC: Preclinical and Clinical Investigations. Harold Keer, Tomoko Smyth, Aurelie Courtin, Keisha Hearn, John Lyons, Nic Add to Reading List Source URL: astx.com Language: English Oncology Organofluorides Crizotinib Piperidines Pyrazoles Pyridines Anaplastic lymphoma kinase Hsp90 inhibitors Hsp90 Medicine Chemistry Lung cancer
30	THE HSP90 INHIBITOR, AT13387, IS EFFECTIVE IN MUTANT EGFR AND ALK-POSITIVE NSCLC MODELS. Tomoko Smyth, Ana Rodriguez-Lopez, Rachel McMenamin, Victoria Lock, Jayne Curry, Brent Graham, John Lyons, Neil Thompson and Nicola Add to Reading List Source URL: astx.com Language: English Organochlorides Amines Quinazolines Pfizer Gefitinib Crizotinib Protein kinase inhibitor ALK inhibitor Hsp90 Chemistry Organic chemistry Organofluorides

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