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Apoptosis / Cell signaling / RNA / Immune system / Inhibitor of apoptosis / Tumor necrosis factor-alpha / XIAP / Caspase-9 / Caspase 3 / Biology / Cell biology / Programmed cell death


SMG1 and NIK regulate apoptosis induced by Smac mimetic compounds
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Document Date: 2011-04-14 05:54:22

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File Size: 1,09 MB

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City

Gibbstown / St. Louis / /

Company

Vibrant Pharma Inc. / TNFa / SMC / Macmillan Publishers Limited / /

Country

United States / Canada / /

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Event

Product Issues / /

Facility

Research Institute / University of Ottawa / Children’s Hospital of Eastern Ontario Research Institute / Children’s Hospital of Eastern Ontario / siRNA library / University of Michigan / /

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IndustryTerm

cancer therapy / cancer therapies / chemical screens / /

MedicalCondition

dependent cancer / DF / tumour necrosis / diverse cancer / NIK-depleted cancer / sensitive cancer / IAP-deficient cancer / SMC-resistant cancer / breast carcinoma / non-small cell lung carcinoma / cancer / Disease / NSCLC / thereby sensitizing cancer / tumour / tumour necrosis factor alpha / /

MedicalTreatment

cancer therapy / cancer therapies / anticancer therapies / /

Organization

University of Michigan / Children’s Hospital of Eastern Ontario / Research Institute / Apoptosis Research Centre / University of Ottawa / Ottawa / Children’s Hospital of Eastern Ontario Research Institute / /

Person

Shaomeng Wang / /

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Position

Representative / Canada *Corresponding author / /

Product

Alamar Blue / H460 / H661 cells / cancer cells / H226 cells / /

ProgrammingLanguage

PIM2 / /

ProvinceOrState

Michigan / South Dakota / /

Region

Eastern Ontario / /

Technology

alpha / siRNA / antibodies / apoptosis / gene expression / treating cancer / /

URL

www.nature.com/cddis / /

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