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CYP3A4
Results: 92

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21	Mathematically modelling the induction of xenobioticmetabolising and transporter enzymes Mohammed I. Atari, Paul D. Metcalfe and Simon Thomas Scientific Computing Group Cyprotex Discovery Ltd. Presentation outline Add to Reading List Source URL: www.opentox.org Language: English - Date: 2011-10-26 07:30:21 Biochemistry Chemistry ABC transporters Transcription factors Antibiotics CYP3A4 Xenobiotic Pregnane X receptor CYP2D6 Biology Metabolism Cytochrome P450
22	Efavirenz (Sustiva) Submitted by Dr. Peter Singer, Alberta Justice Medical Examiner, Edmonton, Canada January 30, 2002 Manufacturer: Add to Reading List Source URL: cal-tox.org Language: English - Date: 2010-09-16 16:37:22 Bristol-Myers Squibb Cyclopropanes Organochlorides Efavirenz CYP3A4 Fluoride Chemistry Organic chemistry Organofluorides
23	Cytochrome Cytochrome P450 P450 Activity Activity Screening Screening in in Low-Volume Add to Reading List Source URL: www.promega.com Language: English - Date: 2011-01-21 11:31:32 Pharmaceutics High-throughput screening Plate reader CYP3A4 CYP1A2 IC50 Pharmacology Cytochrome P450 Pharmaceutical sciences
24	INSPRA (eplerenone) tablets Initial U.S. Approval: 2002 • Concomitant use with strong CYP3A4 inhibitors (4, 7.1) For the treatment of hypertension: • Type 2 diabetes with microalbuminuria (4) Add to Reading List Source URL: www.accessdata.fda.gov Language: English - Date: 2009-03-31 14:09:46 Aldosterone antagonists Amines Electrolyte disturbances Nephrology Potassium Eplerenone ACE inhibitor Spironolactone Statin Chemistry Medicine Organic chemistry
25	DOC Document Add to Reading List Source URL: www.usask.ca Language: English - Date: 2014-10-27 09:23:02 Biochemistry Lignan Microsome Secoisolariciresinol diglucoside CYP3A4 Enzyme CYP2C9 CYP1A2 Resveratrol Cytochrome P450 Biology Chemistry
26	Efavirenz (Sustiva) Submitted by Dr. Peter Singer, Alberta Justice Medical Examiner, Edmonton, Canada January 30, 2002 Manufacturer: Add to Reading List Source URL: www.cal-tox.org Language: English - Date: 2010-09-16 16:37:22 Bristol-Myers Squibb Cyclopropanes Organochlorides Efavirenz CYP3A4 Fluoride Chemistry Organic chemistry Organofluorides
27	Sheetal Agarwal: Clinical Pharmacology of Propoxyphene Add to Reading List Source URL: www.fda.gov Language: English Cytochrome P450 Antitussives Amines Prodrugs Dextropropoxyphene CYP2D6 Carbamazepine CYP3A4 Chemistry Pharmacology Organic chemistry
28	Topic 1 Pharmacogenetics of Irinotecan: Scientific and Clinical Impact of UGT Polymorphism 1. Is the pharmacokinetic and clinical evidence presented sufficient to demonstrate that homozygous UGT1A128 genotypes (7/7 ge Add to Reading List Source URL: www.fda.gov Language: English* - Date: 2004-10-14 14:44:52 Clinical trials Epidemiology Medical research Medical terms Prodrugs Biomarker Irinotecan Surrogate endpoint CYP3A4 Medicine Chemistry Health
29	Incorporating Population Variability into Dosimetry for High-Throughput Toxicity Testing SOT Annual Meeting March 13, 2013 Barbara A. Wetmore Add to Reading List Source URL: epa.gov Language: English - Date: 2013-04-10 16:29:10 Pharmacokinetics Biology EC 1.14 Enzymes CYP3A4 CYP2D6 CYP1A2 Microsome Cytochrome P450 Pharmacology Pharmaceutical sciences
30	Topic 1 Pharmacogenetics of Irinotecan: Scientific and Clinical Impact of UGT Polymorphism 1. Is the pharmacokinetic and clinical evidence presented sufficient to Add to Reading List Source URL: www.fda.gov Language: English - Date: 2004-10-14 14:44:52 Clinical trials Epidemiology Medical research Medical terms Prodrugs Biomarker Irinotecan Surrogate endpoint CYP3A4 Medicine Chemistry Health

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