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Programmed cell death / T cells / RNA splicing / Bcl-2 / Messenger RNA / Melanoma / Vemurafenib / Alternative splicing / C-Raf / Biology / Gene expression / Apoptosis


Apoptosis of human melanoma cells induced by inhibition of B-RAFV600E involves preferential splicing of bimS
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Document Date: 2010-09-02 07:06:55


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City

Westmead / Newcastle / /

Company

COX / Macmillan Publishers Limited / /

Country

Australia / /

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Facility

David Maddison Clinical Sciences Building / Westmead Hospital / Westmead Millennium Institute / Calvary Mater Newcastle Hospital / University of Sydney / 2Westmead Institute / /

IndustryTerm

treatment of melanoma / protein product / in vitro systems / treatment of B-RAFV600E melanoma / also been shown in varying in vitro systems / /

MedicalCondition

Cancer / another three B-RAF-mutant melanoma / Disease / wild-type B-RAF melanoma / mutant B-RAF melanoma / another two B-RAFV600E melanoma / additional three B-RAFmutant melanoma / mutant and wild-type B-RAF melanoma / B-RAF-mutant melanoma / metastatic mutant B-RAF melanomas / melanomas / human melanoma / melanoma / B-RAFV600E melanoma / fresh melanoma / /

Organization

Immunology and Oncology Unit / Calvary Mater Newcastle Hospital / Westmead Millennium Institute / University of Sydney / Westmead Hospital / 2Westmead Institute for Cancer / /

Person

Mel-Rmu / /

/

Position

Major / representative / /

ProvinceOrState

New South Wales / /

Region

South Wales / /

Technology

AIF / siRNA / apoptosis / /

URL

www.nature.com/cddis / /

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