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Medicine / Mammalian target of rapamycin / Senescence / Protein P16 / Sirolimus / Ageing / P21 / Telomere / Beta-galactosidase / Biology / Gerontology / Aging


Volume 5, Number 4; [removed], August 2014 http://dx.doi.org[removed]AD[removed]Review Article mTOR Signaling from Cellular Senescence to
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Document Date: 2014-07-21 12:42:37


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City

Shanghai / Hospital Affiliated / ULK / Suppress / /

Company

Mitsui / AMP / Proc Natl Acad Sci U S A / Vredeveld LC / Hearn SA / Cantley LC / Bodnar AG / Trotman LC / /

Country

United States / /

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Facility

University of California San Francisco / TSC1-TSC2 complex / Shanghai Jiao Tong University / China Gladstone Institute of Cardiovascular Disease / Hall MN / ULK1.ATG13.FIP200 complex / ULK1-Atg13-FIP200 complex / /

IndustryTerm

therapy for aging and age-related disease / cancer therapy / machinery / autophagy machinery / energy signaling / chemical-induced senescence / interleukin-dependent inflammatory network / /

MedicalCondition

related diseases / chronic rapamycin treatment / injury / chronic inflammation / several other related diseases / human diseases / example cancer / age-related diseases / primary Eμ-myc lymphomas / MS / interleukin-dependent inflammatory network / Mitochondria dysfunction / cancers / tumor / Mitochondrial dysfunction / cancer / Disease / human fibrosarcoma cell line / degeneration disease / radiation-induced mucositis / telomere dysfunction / well-known tumor / especially age-related disease / p53 tumor / HT1080 human fibrosarcoma cells / diseases / infection / progerial syndrome / liver injury / age-related disease / disorders / fibrosis / /

MedicalTreatment

stem cell therapy / chemotherapy / radiation / cancer therapy / /

Organization

Food and Drug Administration / China Gladstone Institute of Cardiovascular Disease / mTORC1 association / University of California San Francisco / San Francisco / National Natural Science Foundation of China / School of Medicine / US Federal Reserve / FDA / Shanghai Jiao Tong University / Shanghai / /

Person

Van Remmen / Wei Yuehua / /

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Position

mediator / Harper / Reaper PM / Bishop / Cao / Marshall / /

Product

cyclophosphamide / Cotrim / /

RadioStation

Robitaille AM / Nargund AM / /

Technology

radiation / genetic engineering / cell therapy / apoptosis / DNA synthesis / DNA Chip / gene expression / chemotherapy / treating cancer / /

URL

http /

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