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Gene expression / RNA / Transcription factors / NFE2L2 / KEAP1 / BRD4 / Papillomaviridae / Epigenetics / RNA interference / Biology / Genetics / Biochemistry


The bromodomain protein BRD4 regulates the KEAP1/NRF2-dependent oxidative stress response
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Document Date: 2014-04-24 08:56:35


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File Size: 1,91 MB

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City

Ann Arbor / Santa Clara / Hilden / Taufkirchen / Leiden / Berlin / Jena / Heidelberg / Mannheim / Cambridge / Medium / Darmstadt / San Diego / Penzberg / San Jose / /

Company

KEAP1 / IgG / Life Technologies / Sigma-Aldrich / Agilent / Affymetrix / Qiagen / TOMTOM / Pearson / Flowing Software / NCR / HEK293T / BRD4 / Chanas SA / Ames / NRF2 / Macmillan Publishers Limited / /

Country

Germany / Netherlands / United States / United Kingdom / /

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Event

Business Partnership / FDA Phase / /

Facility

Free University / University of Cologne / Max Planck Institute / /

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IndustryTerm

vision software / cancer therapies / oxidative stress products / cancer treatment / transcription start site / transcriptional regulatory network / de-regulated transcription machinery / transcriptional network / /

MedicalCondition

oxidative stress injury / JE / acute myeloid leukaemia / rheumatoid arthritis / human prostate cancers / MLL-fusion leukaemia / melanoma / non-small-cell lung cancer / primary prostate tumor / prostate cancer / MS / hormone-refractory prostate cancer / asthma / leukemia / tumor / different tumor / prostate tumor / squamous cell lung cancers / cancer / tumors / Disease / prostate cancer cell lines / human lung adenocarcinoma cell lines / common solid cancers / diabetes / severe airway inflammation / acute myeloic leukemia / tumor necrosis / breast tumors / lung cancer / increased metastasis / BMC Cancer / delayed tumor / DNA damage response Inflammatory / neurodegenerative diseases / prostate tumors / central cancer / inflammation / acute myeloid leukemia / /

MedicalTreatment

anti-cancer therapies / radiation / /

Organization

Orlando DA / 5Cologne Center for Genomics / Max Planck Society / University of Cologne / Cologne / German Cancer Research Center / Free University / Berlin / Federal Ministry of Education / Max Planck Institute for Molecular Genetics / Department of Vertebrate Genomics / /

Person

Manfred Schweiger / Gene Ontology / /

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Position

*Corresponding author / Prime Minister / Mediator / passionate scientist / Smith WB / Fedorov O et al / luciferase reporter / HMOX1 reporter / Professor / HMOX1 luciferase reporter / long reporter / empty reporter / reporter / /

Product

penicillin / RelA / P-valueso0 / glycine / dimethyl sulfoxide / Dahl / /

PublishedMedium

Genome Research / /

RadioStation

Choi AM / /

Technology

alpha / Genomics / radiation / bioinformatics / siRNA / antibodies / Biotechnology / directed mutagenesis / Cell Signaling / cloning / DNA binding / human genome / apoptosis / DNA Chip / gene expression / Web Server / /

URL

www.nature.com/cddis / /

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