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Apoptosis / Proteins / Bcl-2 family / Bcl-2-associated X protein / BH3 interacting-domain death agonist / Bcl-2 / P53 upregulated modulator of apoptosis / MCL1 / Bcl-xL / Biology / Cell biology / Programmed cell death


The use of a neutral peptide aptamer scaffold to anchor BH3 peptides constitutes a viable approach to studying their function
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Document Date: 2014-01-30 10:03:40


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Avacta Group Plc / Armstrong SA / Keating AE / Ooi AG / Millipore / Chen LC / Spiegel / 2Medical Research Council Laboratory / Medical Research Council Laboratory / Wilson / pepBH3 / Creative Commons / BD Biosciences / McCormick / Crawford SA / Suzuki / Microsoft / Paschen SA / Parma LP / Macmillan Publishers Limited / /

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Medical Research Council Laboratory of Molecular Biology / University of Leeds / Research Council Laboratory of Molecular Biology / Leeds Institute of Molecular Medicine / National Institute / St James’s University Hospital / Jude Children’s Research Hospital / SQT scaffold / /

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insertion site / cancer therapeutics / degradation products / downstream applications / interaction site / treatment of cancer / molecular tools / restriction enzyme site / chemical stabiliser / /

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solid tumours / prototype cancer / JE / multiple myeloma / SQT scaffold-encoding ORF / colorectal cancer / ORF / J Cancer / human melanoma / Noxa-induced mitochondrial dysfunction / B-cell non-Hodgkin’s lymphomas / melanoma / breast cancer / Leukemia / cancer / Disease / different diffuse large B-cell lymphoma cell lines / melanomas / A375 melanoma / hematologic cancers / diseases / BMC Cancer / chronic lymphocytic leukaemia / Mel-2a melanoma / /

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Brent R. Genetic / Alexa Fluor / Clin Sci / Matthew Adams / Gaizo Moore V / Cory S. Bcl / /

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*Corresponding author / mediator / unified model / RT / player / Fisher / /

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Sigma / BH3 / sterile water / Puma / /

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South Dakota / Gillingham / /

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Molecular and Cellular Biology / Molecular Biology / /

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alpha / Protein Engineering / Antibodies / cloning / apoptosis / spectroscopy / drug design / gel electrophoresis / /

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